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PGA1

Gene
PGA1
Protein
GPI mannosyltransferase 2 subunit PGA1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
198 amino acids
Function
Essential component of the GPI mannosyltransferase 2 complex. Responsible for the transfer of the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly.
Mass
22.383 kDa
Sequence
MVRPQNVHWFIATIVFFIGFVHANTESILYKVPHNFPLKKPRDSSTYARDVNLISSISLSGEAMSQITIEANTTDLELHNTTYIELADLQRDETYQIKVCWSAIHPISINNLQTITIPRFTEFQGTKSDYARILVTFQVLSDSYPSEHAMVPIQVSLITTRLGIPVDIYPTLIVMVLLVAGLVVTRAPHVLNDLLLKF

Gene
PGA1
Protein
Predicted GPI-anchored protein 1
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
132 amino acids
Function
Plays a role in cell wall stability and rigidity. Required for normal adhesion to host cells and for adherence during biofilm formation. Necessary for proper oxidative stress response.
Similarity
Belongs to the KRE1 family.
Mass
13.804 kDa
Sequence
MNFNKFLIIISCYLACVFALANQNDGGDDDSKTKKTTTWVWVTTTIGGQLATISTAYSQKFISTHSSEDAKSVASGEIGLGSLSGSVGGIKTYSQTTITNANIAPSNNNVFLGIESLYTGIVGGIVLILGLL