Protein
Dynein heavy chain-like protein PF11_0240
Organism
Plasmodium falciparum (isolate 3D7)
Function
Acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity).
Similarity
Belongs to the dynein heavy chain family.
Sequence
MTKFSEGHYDILNLIEVKSNIQEKNILGYSIDYTVGGLFLFGGFKIDIEENNGIICNDAYLIHIKNDKAEYETLSIKIKPSIRCYHNSCTLLENYVIIFGGLNSEVPFVALNDLWVFNSLNKTFVEIKLKCKEKNKEKNLQNGINGTNEKGYISQTDDENCSDNKYGENQDYGSNDSDSKDGEDIDKDDSILDNSYVKNLRKYLKSNKSDELHSSDIPCPRYFSSLDLYIIRKNNIEEEKGFKKDEIKIIKNNIIVSNSLNYEYFSLILFGGYGGYDRSSYNDLYEFNILNNEWILRGCKGNVPSTRYGHISFIHGNNLFILGGTNAEISFNDMYSCDLKNNEWSEVDFSYSFNISKVFCRSVLVESIDRNIIFIFGGYNIISDEKGNRKIEYNNIELNMLKLYDTFKLEELKYNIIQNNEENIIKNNNMEEINNMNSNNVKNEIISTKHDIYEDSNISNNITFCSITYDFMDSNLIITDNKKKIYIMNISNIIGPKYAIFNIWPKQCDINGNKKLLFRGKGFTNEGKILVKYKSDDINLYSEGIYINENNIYTIVPNAKNKIKNNICQVQLSINDKCYTTNSCFLEYYYNIDPKNTLIFGSGLLEPVCLQKDNIFFLIAKNSLNEHKKIGGDKFQISIIYEQKSEQYDIKYFVYDLNNGFYIVKYFSFLNDKQMKVKMQNVGKNNNIEQRNNNNDNNDNNNNDNNNNNNNDNNNNNNNNNNNNNNNNDNLNEQLNCNVVQRKNQNDLETLEGPQNISNKNSMNNEDIKSNTNNHMEILDLNGTLKITVKLKDENIQNSPFFLKVDNNLKDKIIYVKQFINDRLENLLRKGECLFDLIKNKNMNTNNLIQLNINIDHFLNTFPKAIHDINIIEQYILYGLIDIDKIKNVITNLHEEDNLVNASQEEEIYIDKEIHELINNEKFKNDQTDEMGEYTATTTNNVKHTNNTNNNDTHITDTLTHINENNDTRNNFLKVKDNHKIVDFINENKLKFLDYIDPNIMKKLRNYINLLNTEELNLKNKKDNKKIDDSNKKDLLGIKKKRSEDKFHLDNNLEKDEKKIEVIKNLLIFYHKLKTVCLSKKEKELKDEFIKEEKESIKKLKLNYNKFVNIKKNLEVSNVYLHNNGYDSSLKELETTKKYLIEIKDEVTKIKQISDNIIKIDNVEELNKDIENLNNEIHEIEKMWLFIKKKEEILNEFFFCPFKDLDVEDFDIQIKKLQNDFKKIKVDRKHNICKEETLKLKEIIKFISVLCEIKKPFIKDRHIKEMENNINEEKEKNKEEDKINIIIDDSTLTIYFYKLNIMKYHDTIEEVIIKAYNEKIIEETINKFEDYWDKIYFKKKEYKNNILLTYIDDICIDTIEEHQVTLQNCFSSKYFLFFSDELNLWQKKISNIYEVIQLLKDIEKLWIYLQNMYIYSEEVKKELPLYSKFFLTINDEYLEMLKQIIDNNIKVVDFSNEGGIIEKLEELKVKLCKSEKPLNEYLDSKRKSFPRFFFISSTDLIDILSNGNNFKLVNTHVQKIFLSIRKFVTKNEQLTDNEIQNEVKLNNQETITEEKNKNANENSNEIETNKYNKKEELTNNRDGDGDDDDNIKNDKDEKDEKEETIIKLISSYGEEICNFHEGLVLKGKVECYLNDIIDHIKYTLKYYITNLFRLKDLFNNEKEKWIDENYLAQVFILCNTIFFVNDVENILIKKDINIYEELNKYYKNHILQLENVIKKVQKKLTIKNRIKIMCIITLDTFYRDVLEVILKNKSSISINMFDWQSQIRMYPFFKNQKIYEQNENQTEESNLKLDNKNLDNEHQEGKQEYNNKNNDNDNNNNNNNNNILNNELSKYTCLTHFKDLYIKIKIMDCSFNYSYDYIGNYQRLVITPLTSRIYITATQALSLYMGCAPAGPAGTGKTETTKDLSSFFGKNCYVFNCSDQLDYKSMGNIFKGIGSTGCWCCFDEFNRLIPEVLSVCSIQFKSILDCKRNNNNVCIIGSDEIIVKKNCAVFITMNPDYLGRSKLPESLKILFRPITVIIPDFNKICENMLMAEGYVNAKYLSIKFTTFFELAKSLLKDKHCDWGLRSIKSVLTKAGDLKRNYPDVDENKLLYSAIHDINIAKISSSNCPIFSGLLNDIFFSNQNDITDINDINDINENKKEKDNIEELKSDNVKEEKKTKKKHLEDNNNNKKKELFNLNNIEKELMDICKKNHLFGLNYFVKKIIQLNDIMNIRHCVFIMGEAGCGKTTLFNMLMEYQKKQNLKTVSIRINPKSINIDDLYGNVHIKTREWKDGVFSKYMRNYSKKDDCDKAYIIFDGNLDSHWIENMNSVMDDNKVLTLSSNERILLKNHMNLVFEFSDLMFATPATISRAGLVYFSVDPNDLWKNYFLSWIDKHDNFNSNIKKLFEKLMYKYVEPTFSYLSTLQTSIKISPMSHIQSLSALLDILLIDNNYESVEHYFIYSVIWCFGGFLGEKDNVNYKKSFDKYWKNTFKSIKVNRKISVFDFYVENNKFKEWDEAEITNELKQNYVLQDDIFIETIESYSYKYICKLFLKSDMPILFIGKTGVGKTQLCKKILNEEKEEFKSFYMIFNYYTTSKNVQTLMQSCLEKKSGKQFSPPYQQKLIYFIDDINMPKCDDYNTQSAIELLCQYIDTNSWFDLEKLNLIKILNTKLISCMNYNRGNFTINPRLIRHFFILNINFPENNTVNSIFSVLLKNHFNNFKQDVSDLIPSILKSTISLFYNIEKTFKRTATYFYYEFNLRDIHSIVKGLLTTTPVTFQDCDKLLFLWLHECERVYSDKLNKKDKNKYKKIITDIIKKMYNKYEINKFVMKYDSTLLFSNFHKGSHDKTYDICKNMEELTLFLNEELNEYNNSYNVNIVLFSDAIKHICKLIRIVDNLKAHALLLGIGGCGKTTISKFSSYISSKTFFEMDFSAHCTDNDIKKYLQNIFHKCAMKNEDIVLFLKESKIHDTFFIYVNEYMCSNNIIDLYTKEERDYIIHNIRNIAKADGIEQSDNNIFDYYIKKVNDNLHFILCFSPTSNNFRDKSNNFQCILNNTMIDIYDNWEADSLMCVGKNYVSNIYMNINTGDILLDQEYINLKNKNIEKDITLGNKQIEKNYIPTISTNDGDDHYKDMDKTNMKNGDITTTINNIPIDNNNNNNNNRDNIDGNNFFKNREGNDENMKRKVYSNNFTNQNDLNTNITNNNNNNSNNNNNNIYDKNDSILKEEEYVNLKDIITEYLKECYEDLLDISSFYYSHERSHIYITPKLYLESIKTYHIMLLKNITNINNKMNMLKNGITKMNETSSNVENIKNCLKDKKKISEEKMEAAEKYAIDIGNEKMVVKKESDLADIEEQNCLEIQKKVLKQQEECENDIRLGIPLIEQAEEALNTLNKKNIQELKTLNKPPPGVEDITAAVMQLLATIDTTISIDKFGKIKDRSWKSAQKMMINPEKFISLLKDYKNKIDENLVPDCNFKYVENLINLPHFNKNAIQKKSKAAAGLAEWVLNITSFYKIIQNILPKRILLDNTKKGLEEANEKLQIVREKVQSLKAKLSELISQYDHAIYERDLVILEEKKLKTKLELSIRLIDALSSEEISWSKQYESLKKKKKTILTDILLSSTFVTFCGGFTKKYRNKIMTNCVDTLKRKNEIQNNIFNNMLKKINNNDQNFINNNNNNNSSNNNSTNFGYNEDPQKKDNHNNFDISNKLNIKNEKKDNELGNDNLKKEEMIYDIFLVNNFNLDLLINEEVLSKLSKQGLTLNSVCIENNIILENSDKFPIIIDPQMESLKWLINSHKEKSEKLIITDINDKILLKKIEECISFGYSIIVENADEYIDNTLYNVISKNIIKRKNNYYININDKELMFHPSFYIILHTQLSNPHYQPEIQSACSLINFTVTPDDLEEHLLSITLENEFNHLSKKKKKLSLLKYDYMCQLSFLQSSILQKLTDAKGDILEDVSLIENLEKTKLLSENIAKKTEIVKNTEVHINTIINLYRPLSKRGVMYFFILQKLKNLHSFYFYSLEIFLKIFIKCLNDSSPNRSPSKVNQEQEYYLKSEDNDFNDDYLGSTKEEEKMEDEEKMEEEKVDEEKMEEEKVDEEKMEDEKVEEKMEEEKVVEENTEDEKAIEINTEDEKAVEKNTEDEKAVEKNTEDEKAIEKNTEDEKAVEKNTEDEKAVEKNTEDEKAIEKNTEDEKAVEKNTEDEKAVEQNTEDEKVVEENTEDEKAVEKNTEDEKAVEKNTEDEKVVEEKIEDEKGEEQKAEEENVGIEEVEKVQIDDYKVSEKKGENKNCTYEENGKIDKDKEDDLEEEEDFENDDFTNEETKIDKNEVEKRVNMLTDLLNIKMWMYMDKGLLERDKLIVKCLIMLHLEKLNDKISEEEEEIFINPKYKLSNNNITSIRNKKENESMEKKLMNKSFINEELYEDCKNLENLKDFENITESFESESMSWKQWFLSEKVENEELPRKYNNIKDFSKLLLIRVLRKDRFLIALKNYITKNIKMTNDEKNNTYALENILDEYIDNKTPVLFLLTTGYDPSKEIEDYINKMKNNAIKKNDSNKKESNKNNIAYVNISMGQGQENIALKYLKEISKCGGYIFLQNIHLMTKWLKEFEEILDKIFLDAHVNFRLFLSAAIPNEKDTKLLPEKLLKKCFRINNEKSYSLKDNIKCCLDKFENGQYDDKLKTVILGLSYYHSLLLGRFLYGKIGFSQSYSFNDNDLEISFNIIKRYLKTYESFPLADVLFLIGEIIYGGHITDIWDRRINKTYVKNILKEIYRNIISINEKNKNINMDFHHPNDSNNNYNDDDNNNSHKNNKNNNNNNNKDDDDESNNSNDNEEENEEKLILKNTKHNILFDVFKFPDCSKYNINQLKKYIDEKLNKEQTYLLGLHINAEIEYMKNECSRILQTLQELSNKEIASTESYKKNTKIIKKEKPGDNKDNKYTHDQKKETIHKEEDDEDEKHSGSNKSTKIIYDIINHLLNELPDKIDTNDLKIEDSQTNTFMVIALKEAEKFNKLIECINDTLIEIKLVLDGILNMNDKIQNTIKSLMLHNIPHIWINYSYPSKKKLMPWFENFKLRIIFIKEWISKIRNNIFLPNSVWLSALFNPISFLTAIKQKFAQENKVPIDKLKLKWQVTNITKLEDLNNKNNALYIHGLYLQGASWFINSKNDTFTFDKDNINDNVSYGNIIESVPKHIYYSMPLIYVYCISNEQDELLKENMEYRSLDTPLYVTSDRGNTFVCSIDLNLEMEDIEDKWILAGVALFLSDD