Protein
Polyribonucleotide 5'-hydroxyl-kinase PF0112
Organism
Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Function
Polynucleotide kinase that can phosphorylate the 5'-hydroxyl groups of both single-stranded RNA (ssRNA) and single-stranded DNA (ssDNA). Exhibits a strong preference for ssRNA (By similarity).
Sequence
MEVNKASLTYDVPEDREYATKRILSLKRPSKIMVIGDVDTGKTTLIVYLANELISRGFKVAIVDADVGQKGILPPATISLALADMKFSSLSELKPLIHYFVGSITPSQFFGEMIVGTMRLSEIGKKFADYVLIDTTGMIYGSGVELKRLKIEAVKPDLILALEKKEELNPIVSGFEDKTIKLKVSENARSYSRSERRQIRQEKWRKYFENAKIVSFSLENVVVTGTSLFQGSDIREEEKSLLERLFKWVILHGRRIGDKYFVVKADVAEVPRVVDKNVVRYFDFEKLSNLLVGLLNEEGLCLGVGIIKGINFGEKRIDILTPVSEIENVREIRFGRIRVREDGEELGILDREAL