PEX8

Gene

PEX8

Protein

Peroxisomal biogenesis factor 8

Organism

Komagataella pastoris

Length

713 amino acids

Function

Essential component of the machinery required for the import of both PTS1 and PTS2 (and perhaps all) peroxisomal matrix proteins.

Mass

81.008 kDa

Sequence

MYRLGSQGRSIQSQLQNGDSSSGRPLQLQGTGMREAQRIPQQLDYLLAEIISPNEDTNVIGYLAYYYPKLKNEQNVALLTDFFLRCPTYFSHSNVVSLRNNYPVMEAFNYIMTTKFKVSQPTVPFYRFYAAVLASLLNCEKTDPSHHWKLIPILTGVLLSIKGRDDVELYPDHSRSIKGSDTAVAQLLQRCLLRFYQSGDARSYDLNALVIISMSCALDYVEDDTIKKILYCFNYTRAIIDLIYYSPYGLNDSDIPLLSDSSVNSQSFDQLLNNNPALKHLNRLSFLFERTVKLNDGSIQSNLNDIDISLNKMQSFSEKLSKKISVLDDDSSKGVGQLLRQCLYASIIIHQAILTTFFQLDNADYTKYFLPSFSRKILSILFNLFFIVDRIGTGGFQPYNFVYLTCLQGIIQYDMKTAESLVKTFTTGINYSSLKDSEVARAKLLFTLNLMEQIVNICSDDLRLELIVPLVEDLVNNKNACVDIHNHVFKSIFESAHSVILKFFTVVDSSVKNVDYETNVTLVSEKIIPYLTLVIDQFPEFLSINQLDIAIETISRTVFPDSPIYSYDKNISSMFLNVLFNKCLTVDNDELVELPAIEAVVAPKNDEENNTSDAQDGGPKELQSLNDLKSRRSALISALISVFPLIPVKDYTKWLSIAFYDLIVATPERTERAFLQERLWDCVVGTNKYDPQKGNLGIMWWYENVNAQSTAKL

Protein

Peroxisomal biogenesis factor 8: PEX8

Gene

PEX8

Protein

Peroxisomal biogenesis factor 8

Organism

Pichia angusta

Length

650 amino acids

Function

Essential for peroxisome biogenesis. May play a role in triggering the protein import competence of individual peroxisomes. It may interact with PEX10.

Mass

74.122 kDa

Sequence

MQPWYHKLGRQGRQLAEQWQTDAEPWGVATPTPLDYLFDELTAPKPSTTPDKVLSYLAYYYPKLKNENNVELLTLCFLRCPLFFNDAQLVSFSDNYRVIECFKYIMDKKFQISQPTLPFYRFYNALFGALAKVVADSACAWKVVPVAVGCLLSVDSRNDYDRYPEHFQLIATVDAKLVDMAAHTLERSMDGPLSNDLLCLNVVALSCVQDKLVDSQLLRILRVRSDILKILTELTFNSPYGLDNGRLLTKSNANTPIVVRHLNRISFLFTKLTSIHPKIVLLADDLDLILNRIQTFSESVLSIPNPSETQWSTLRVVLFAQVMMFEGIMARFFQINNHSLNSTVLPTLCRKILTTLFNFNFVVDRIGTGGFESYNFVYASCLSTLTSYDIPTAETLIKCWTSSVAFKKVDNSATERGKLLFDLQFIENVVNLVSDSLKFEFIIPIVQDLIGNAQDQAVLESAHSVMLKYFTSVDTYNEAQLVDYTNNVKHVGAQLIDYLTLSLDQFPARLSLSQVGIIVETLAKITFPDTAVHECDPELYRELLLLVYNRCLVATSEELPNVQAPPKTRHGAFTSLLIRILPLIPFDEYQSWLERTLSLAFRTVGDERTYLLDLLWDSILGTNRHYPQKGYVGIQWWYEHVNESQEKAKL

Protein

Peroxisomal biogenesis factor 8: PEX8

Gene

PEX8

Protein

Peroxisomal biogenesis factor 8

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

589 amino acids

Function

Required for peroxisome assembly.

Mass

68.165 kDa

Sequence

MFDHDVEYLITALSSETRIQYDQRLLDEIAANVVYYVPRVKSPDTLYRLVGALFRSQFIVQLPPLRLLHIVKDVFLWKLEVSEPTLPISKFYLVWNAVFESHRATWNLSQLMVLDGVLVTYPSFKQLNNAYFIDESSNKTALYYRNWKLQLFSPIWAQLWNTAIVRANLSIQHCLLIALALLFNQSNRSALLHGVDVSWNLVTEKLLDLLEEYVHGIVQPMEIFSTDSVLSTNLNHLASCLTSSITRSNEATLVNSVRKLERICRYLSDTVASLKEQQLDFKFQNVFILIILALKELSAMNMTILPNHKDTFYSMICLSLFHVHVLTQKIGTVGFPSYDYVYDNLVTYFIVMDDLSKITTVLELMKRNNTKQDPNKLVFYINFLNKITNYYGCRIRLPFITEFIEPLLHFDVFFSGKTGNTLDIEIKESIHTLTITVLSIDSSYSSQVAQWQVSRILVYLKMSMDQFIAGKLSANQILLIFGHLSTQLPSLHNYNKHLLRDSLHETYIRIVNVKNPEKKNVLIECLIVQIAFINNPHHLIGWLNICLQLINTHNKKLLQQLWEMVSSLESSLAIDWWYTTVLSSQSSKL

Protein

Peroxisomal biogenesis factor 8: PEX8