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PCO2

Gene
PCO2
Protein
Plant cysteine oxidase 2
Organism
Arabidopsis thaliana
Length
276 amino acids
Function
Oxidizes N-terminal cysteine residues, thus preparing the protein for N-end rule pathway-mediated proteasomal degradation. Controls the preparation of ERF-VII proteins for degradation via the 26S proteasome. Not active on Cys located inside or at the C-terminus of a peptide. Represses the anaerobic response.
Similarity
Belongs to the cysteine dioxygenase family.
Mass
30.82 kDa
Sequence
MGTDTVMSGRVRKDLSKTNPNGNIPENRSNSRKKIQRRSKKTLICPVQKLFDTCKKVFADGKSGTVPSQENIEMLRAVLDEIKPEDVGVNPKMSYFRSTVTGRSPLVTYLHIYACHRFSICIFCLPPSGVIPLHNHPEMTVFSKLLFGTMHIKSYDWVPDSPQPSSDTRLAKVKVDSDFTAPCDTSILYPADGGNMHCFTAKTACAVLDVIGPPYSDPAGRHCTYYFDYPFSSFSVDGVVVAEEEKEGYAWLKEREEKPEDLTVTALMYSGPTIKE