PCO1

Plant cysteine oxidase 1

293 amino acids

Oxidizes N-terminal cysteine residues, thus preparing the protein for N-end rule pathway-mediated proteasomal degradation. Controls the preparation of ERF-VII proteins for degradation via the 26S proteasome. Not active on Cys located inside or at the C-terminus of a peptide. Represses the anaerobic response.

Belongs to the cysteine dioxygenase family.

33.014 kDa

MGFEMKPEKEVLELISSKNQCKSNPNSVKKKNKNKNKKMMMTWRRKKIDSPADGITAVRRLFNTCKEVFSNGGPGVIPSEDKIQQLREILDDMKPEDVGLTPTMPYFRPNSGVEARSSPPITYLHLHQCDQFSIGIFCLPPSGVIPLHNHPGMTVFSKLLFGTMHIKSYDWVVDAPMRDSKTRLAKLKVDSTFTAPCNASILYPEDGGNMHRFTAITACAVLDVLGPPYCNPEGRHCTYFLEFPLDKLSSEDDDVLSSEEEKEGYAWLQERDDNPEDHTNVVGALYRGPKVED