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PBN1

Gene
pbn1
Protein
Protein pbn1
Organism
Aspergillus oryzae (strain ATCC 42149 / RIB 40)
Length
543 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
60.188 kDa
Sequence
MRRRITFVQRPETPFSLDQAVLTPDALALHGIDGAREERATFSVDELPEELSDVLKQCHQLHVRWASERRYDAVAPFSSRVSPGLHVFYTPVDGSSEENKLKSLCALLKRAFDYGLKCKSPETLEESFITPPILSTRFASTAAFQYHSLLPTLDNLVAYIENKICSSSDEQCLRYAASIRSADSVDINYDSISHSLTVLGYWSQSPKNGWTDEIRRHAAGTDQVEVGLLGTEAATEPEDIKMGGLLAVVGKDDQLSMLSSGLPSEFGVAYGYGTDDSWAEPTLFSFPSRHQPLPEDATYSISFTSPTGLHPTMTISMPPSSLNSPPAPPDATCALHTYLTLPSTIFGDKYQLSTTDPLFLDSHNLVALHAVAGETDLEAPDWFVSRWGSNWLLELATPSESDQVPEEWNVTIPLHLRYLRPSESGYRSASVPWPVVFWACTAEDGTKMGVNPFDRVNLGWEGLFGTRTMFYQLHPSSDRLVEELEVPVLQLDDKGFFQSKAIELGTMIVIGLGSLWVLWKLGAIAWSSGTRPQRKSTKQKKSE
Protein
Protein pbn1: pbn1

Gene
pbn1
Protein
Protein pbn1
Organism
Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Length
526 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
58.675 kDa
Sequence
MRQRITYIQKPSLPFHPSQTTLTRDSLYVESLDAAREERVTFSFDELPSELWQVLRQCHQLHIRWASERAFEAVSPLSSRISPGLHVFYSPVEAGRAKRDSEGREPLCTLLKKVFDDELRCESPEKSFITPPILSKRFASTTAYQFYELLPSLGNLVTYIQQKFCGTDDKCHQRAASILSADSVDINYDSISHALTMSGFWSQAPGEQGWTETIGKHEGGTDKVEIGLLGAEPASEPEEIKVGGLLAVVGQDEELKPTLFSFPSRHHPLHEDATYSVTFPPPTGLHPTMTISIAPEALKEPPRRPDATCALHAYLTLPSKLFGDKYQLSTTDPLFLKSHNLASLRAVAGETDLEAPDWSISRWGSNWLLELASPSESDEVAEEWNITIPLHLRYLPPSESGYQPASVPWPVVFWACSAEDGTKMGVNPFDRINLGWEGLFGPRTMFYQLHPSPSPEGGNLVEELEVPVLTLKENSGIFNSQVIELGTFAVISIGFLWVLWKLGLVARSSGIRPQHQRNPGKRDKAE
Protein
Protein pbn1: pbn1

Gene
PBN1
Protein
Protein PBN1
Organism
Yarrowia lipolytica (strain CLIB 122 / E 150)
Length
523 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
59.01 kDa
Sequence
MRRRATILADLQQHGDKISFKPGDNNKSKLTVSVNAPRQDRFSAPVSNADLDVLNHVADVSVAWGRPSAAQQPVLFAAAYEPGLHVTVVKKQASEPRKWGEEKPSEAAPELVHVAKFLEEQLGLPVDPKTFIESRSDYTYYDPLVGPEAFGHFVDKHSACSDESEEFVNDLDTFNYAQSASFHIDHDKKELVTEVTIPDLEHYFNQKKQHISRACKNDRLEVGIFDLNNLATSYAFRGVAELKGLLHDSTKEKPQETFLVIEPRHNIGAGSVSVDFERPVGLHPKSELKLRHIAIPTDHNDENDGVKHCRLFAKYSAPSSIFFDKYQLADLERTTSEHPNGQGRLLALWGEADLEEPRYHTEGWGSEALVEIFPITDAPEGTPFNLNFTLPLHLRYEEPKEGETYEPNEAPWPLVFWVCAETDEQLANFKQSPFDVTHNSYMRLFPEGVSYHHIGPREANGRGFPLLSTSWGTPVADIDRFAAVRDYTSIMMVAGFLMVTIAILRKVFRGKAMSEELKEKKEQ
Protein
Protein PBN1: PBN1

Gene
pbn1
Protein
Protein pbn1
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
501 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gim-1/gpi14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
55.527 kDa
Sequence
MRERITFIQKQGDSIEPTTLKIKGGVLNGPEIQAAREDRLTIAIDELPKDLQALLGTAHELHIRYVSSQPYEAITPLLARLPPGFHLFYTPAGQADATSPALCLALNQIFGNVQCENPEKSFTTLPRDRFSHSAAYQFYQPSVDLSPFIALVKEKLCSSSKDQSCAARADRLANASSLDISYDAISHAVKLTATWPYQKQEVHATSRPQTRTEVGVLNSDRPGHLEPHELGISGLLTVLGQDKKPSATMFAFASRHRDAESSFSAEFLEPTGLHPTLKLRLESSKPPIEDAYCSPHAYFTLPKTIFADRHQLSDDLFLASKNLTGLRYISQPVDLEAPEYVEKRWGSSLLLELSPPEHEESKSWTVQVPLHLRYLSPAEGGYTDIQVPYPAVFWACAAEEGTKFPNNPFEKANLGYDGLFGPRTVFWHVEPRPTIGSRLSNMIKVPVLDTNKAEWVSGGTGLAVLLGFAWIMWKLFGVLSKSGYQNQPSQAAEVVKAKKNQ
Protein
Protein pbn1: pbn1

Gene
PBN1
Protein
Protein PBN1
Organism
Gibberella zeae (strain PH-1 / ATCC MYA-4620 / FGSC 9075 / NRRL 31084)
Length
493 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
54.512 kDa
Sequence
MRERVTFIHNDYSLDPEALDNQDAGLLGPQIETVRQDKLTIPFGELPSELTDILQEYEALHIRWASPVKSETMDPFTSRISPGLHVYATPVLPSSCNPTKLCSWLQRFGPLDCSKPEAFTEFQQSTSTSPSFSFYEALEDLHSFITTSSQEFCPELDSVCNARLRSLLTASGLDLSFDKAANALVVSALWPLRPQTVAVPASSARRVEVGIFINDRSQPNMKENELGVAGVLSVLGDQKKPSPTIFTFPARHRRDGSVFTSKFLTPTGLHPTLQLSFNSNKLPSADGECAPYAFLTLPKTIFADRYQLGDELFLASKNLTALRYTTLPVDLEAPAYTTETWGSSILLGLAPPDPGTEKPWSVEIPLHLRYLKPSATGQVEIEIPYPAVFWACSSEEGTLESPFDRLHVGYDYLFPRDTVFWHANPQPENGSRLMNRVTVPVLDDDGVGSIRSGTAIAVAIGFAWVMWKLVSVMLKSDRAPAGVTKETKQKKSH
Protein
Protein PBN1: PBN1

Gene
pbn1
Protein
Protein pbn1
Organism
Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100)
Length
489 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
54.773 kDa
Sequence
MRRRITFVQRPESPFHVDQAVLTSDALSITHLDAAREERATFGFDELPAEIWQVLKSSHELHIRWATERPYEIGAPFSSRISPGLHVYYTPGTARETGVGLCSLLKTVFDESLECQSLRYYSRLPSLQNLVAFIQHKFCDRSDEKCVHHAESILSADSVDVNYDSISHALTVSGYWSTSPGQGWTEQIRKHAADTHQVEVGLLGVESATEPEELKMEPTLFSFPSRHHPLPADATYTVSFPAPTGLHPTLTISMPRASLRRPPAPPDATCALHTYLTLPSWIFGDKYQLSTTDRLFLSSHNLAALRAVAGETDLEAPDWVVSRWGSNWLLELATPLRPDTSPEEWNASIPLHLRYLTPSESGYRSAAVPWPIVFWACTAEDGTKMGVNPFDRVNLGWEGLFGARTMFYQLHPAPAEGKDRLVEELDVPVLRLREDAGFFQSKTIELGTVVVVGLGLLWVLWKLGLVLWIAGTGRSTRAQKRTDKHRKAE
Protein
Protein pbn1: pbn1

Gene
PBN1
Protein
Protein PBN1
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Length
481 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
55.568 kDa
Sequence
MRQRTTIYNPYSSHDGIITNLNRTNFQLSSIPNHLFTIENKYTITTTTTQPNKSSLYSAIKELRIQTKFNNNESGIPIFSFHYEPGLNIYAVPQSNVDKLEFWQQVEQLIMELLGIKLSSQQWIANVNSFYYHDIQPQPLLNLKEGWKFNLHPKSNYDYIYNQDKIIIRELLTNVSEIEFNLESGIYKEIGLFLIDEKISTNDDLNLSGIRVILDEDSNTNNKEESIHKTMFHIKPRHRSFDDSTTITTTKIIPQGLHPILSTELNTTTIVIPTDFDVEECKFYYYLNLNKSLIFDQFQNIPIGSQLIINNGNKNLELPEYKINQWGNELLFEFEFDNDNDIPHHINLTVHSRYQLPQNNHSHSQISNVLNSLPNIFIGCNVKEGNLLDKSPFDTKRDVKIGGNYEIYFTEDTVFYHLQNSDNSGNSGSSTLLEINIPHGKTTFDRVNNITSLGLLIGVLMILYAISIRVFMSTTSKTKRD
Protein
Protein PBN1: PBN1

Gene
PBN1
Protein
Protein PBN1
Organism
Debaryomyces hansenii (strain ATCC 36239 / CBS 767 / JCM 1990 / NBRC 0083 / IGC 2968)
Length
450 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
52.197 kDa
Sequence
MIRQRTTIFNPTKSNDGIIEAVDSSHLQLSSIDYQCEDKFILQTPKFKYIDKLRIQLNQFHSESILFSKYQAGLNIYCKPKIGDEGFNQEEFFNELNQMMTNLFDIPRDGWINSLDTLFYHEPSTGSESFIEYVRKLTGNESNVNLEVSPNIEYVYDGEKVVLKLNGKSLANTTITKNSKFNKEIGLFLIEKGISSEDDIVLSGLRVILNGDDDKNEEYLQKTLFHVKRRQRQSRGTYSSQVKENGMHPFLKTDIHSDIPNDEDLIQCKLYYYLDLNKSFFVDKYQLPKEFTSYVNFGNTDLELPEYKINEWGSEILMEIENNQQISLPLHSRYQLPNNESSIRVTGINDPLIFYGCDVKDSYLLESSPFDNRLDIGGNYERFFTDNTVFYHLSSHENQLQINIPRGNESIKKINFVTNLIFIAGVVLIFYKIVQGIFKRNPSAGTRKNE
Protein
Protein PBN1: PBN1

Gene
PBN1
Protein
Protein PBN1
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
416 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
47.746 kDa
Sequence
MESVRHRIALLFANEADIQDVETVEDGVIVFPNSNITIQDRWTYAIDYELDSIRRISWRNPSSTRQFSVIESRLAPGFNIYSNDKEARLNLFGIQPVYSPMYKSLHSETWKSINEILPGGKNLNIPWNPELCDYDILITANTVQVFSYCSLVEKKKFVKDAGKVEIGLFHVDTEDEEDINLSGLRCTWEDTSNNIGKCEKTTLFYKPFHLYVDDSSDIAPITIENTNGLHPKMKIDLSGIRKDKDCRHFVFSQLPSEIFVDKFQSPGSIVFGLDDLELPDYKVNSLSWGSESIVTLKEGQINEITYFSRYLEPKERASNKTVGFEPILFKACQVGKEEDLSNPFYSRSLGYEAYFSENTKFYHINSTSVHVNIPYPNKNDIGNIEYTTFGIVVLAICYLIYKLLRPSRKLSTVKRD
Protein
Protein PBN1: PBN1

Gene
PBN1
Protein
Protein PBN1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
416 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Aids the autocatalytic processing of PRB1. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14.
Similarity
Belongs to the PIGX family.
Mass
47.923 kDa
Sequence
MVTRHRVTVLYNAPEDIGNHMRQNDTHLTVRGGSGVVLQQRWLLERTGSLDKSFTRITWRPRADLARSLSVIENELSAGFSVYSNSSDVPERFITNPVYNSFHSEKFDIEQYLPPEVDLNLSWNPEDFTYDISVEPTQIQIVEYRLLKQGEEFTIARVKDEKLEVGVFFVDASDESDVDIGGIRCNWRMDDGKMERCQKTSLLYKQGHIAYNHSTTTTSLYLNEPIGLHPKIMIDLTDFEERPKCMYLMHLQLPLELFIDKFQSSPLLLFGEDDLELPEYSLRDKAWGSESIFELKAGTMNEVTLHTRYIEPSNNKGDKLEVSFDPEVILACDTGDNKVSRNPFYKKGLGYESLFTDDTTFRHLNSTTLLVPIPRPDTKDYSKIKNGTLLCLLISIIYIFSKVFGNNKKKRSVKRE
Protein
Protein PBN1: PBN1

Gene
PBN1
Protein
Protein PBN1
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
414 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
47.378 kDa
Sequence
MSVQTIQSESFIEEKRRITVLLDRDGRSVEEKVVNRDGVITIPNQSGHVQDRAVLFVPQLASRPDFIHISWKRNAEADITPIKSYIPYGFNIFTNSSGSIAKFIDTPVGKVYYSDTFEDNALSKWFPPEFVDQLLRYSEDNDLDITVTRGRVEVNRYYELTDDNLFPLNGTESVKTEAGIFQVDTEDDTDTSLSGLRCTWHTGSGALNKCQRTLFFYNQIYADKSSLSEVSLTLSEPVNLHPVVQIDLTSKRPIHNCEYYAYFNLPKYFFIDQFQSIPTLLFGEHDLELPEYKLSGFGSISLFTLQPGSINEVTLHSRYIKPTNDGSAFFEAAFTPQVFYACDTSIELTKRSPFYTGKIGYEHFFTDNTKFYYLNSTKMTINLPKLDSSDNLCIQLFTLGLVLFSVLYLIRKLF
Protein
Protein PBN1: PBN1

Gene
PBN1
Protein
Protein PBN1
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
413 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
45.418 kDa
Sequence
MQSVRQTVLFESEEAWRAGAEQNATAITVHARGGEVVQTRRTWAAAGGPRVRVTWSGGRTVSEVSPQLAAGLSVYVEGGAHVSRDFVQARGQAVFHSAQLELDAVRAWWPRELAVQPEALRWAECAYDIELGRQVRVDEYCALRAGETVALTAAAGGTDEAKVETGVFYPEISDGADVSLSGFRCTWLRDGSGRTDTCQKTLLMYKPAHVHMPEPAVGIELVQPVTLHPVIEVDLSSVSASGPACAHHVFLQLPAQLFVDKFQQPPELLFGEDDLELPEYKVEAWGSEVIYALEPGRVNRVQLHSRYARPGPGRRYEVVPLRPYVFEACDTGSADIAENPFYSKGMGFEAYFTADTVFKHRNSTRLNIPVPRGNSNDFPSIQYVTVLSILFSVLYISYCLFRRPVAASARASG
Protein
Protein PBN1: PBN1

Gene
pbn1
Protein
Protein pbn1
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843)
Length
332 amino acids
Function
Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gpi14 (By similarity).
Similarity
Belongs to the PIGX family.
Mass
38.483 kDa
Sequence
MDLQRTNQDTGTTTLFKVVISNTVNYLPKGVWILRNNTIDSLSIAKQFREIKNNINISHLSRENYWVETPFGKVFHSEVVSEEFMQIFIDKGNKALNNEEMIFACMSEKGWNVSLETVPNLDIPVGSYETQLGLPVGLHPKLHVHLKNLHKPEDECSLQGFMYIPPTLFIDRYELSNIAEMHADNLGHVLGIWGETDLEAPSYKLNGTGSFFWFDIYTDDGLLQKDYIDTIIPLHTRYQSPLKGQTYLKTSLTNPKFFWNCDTEDKVNDFRFLFSSKNKYTLQNDPTTLSISIPIADLSYKHVVEWVTNGVAIFSFFYLLLYLWKRFRYAKD
Protein
Protein pbn1: pbn1