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PAS_chr2-1_0323

Gene
PAS_chr2-1_0323
Protein
Succinate dehydrogenase assembly factor 2, mitochondrial
Organism
Komagataella phaffii (strain GS115 / ATCC 20864)
Length
190 amino acids
Function
Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer.
Similarity
Belongs to the SDHAF2 family.
Mass
22.414 kDa
Sequence
METTCGLPVLPQKISVNFMLRETVDDLGLSKSVTFFLLNSPIMLRLFQRTQFQGSKTCPRVFSKSFHSLPFLRQELILKVEPLKRDNESEDVKRRRLVYQSRKRGILETDLLLSRFAKRYLPTMSVEEMEEYDDLLNELDWDIYYWAVKNYEVTPLPEKWKDSKILAKLQEMSANNEGEILRMPNLDDSP