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PAO1

Gene
PAO1
Protein
Polyamine oxidase 1
Organism
Oryza sativa subsp. japonica
Length
512 amino acids
Function
Flavoenzyme involved in polyamine back-conversion (PubMed:24105034). Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and its acetyl derivatives (PubMed:24105034). Substrate preference is thermospermine > spermine > norspermine > N(1)-acetylspermine (PubMed:24105034). No activity detected when putrescine or spermidine are used as substrates (PubMed:24105034). Plays an important role in the regulation of polyamine intracellular concentration (Probable).
Similarity
Belongs to the flavin monoamine oxidase family.
Mass
54.112 kDa
Sequence
MVAKKPRVVVVGAGISGLAAAHRLCGAGGDRFEVAVVEAGDRVGGRILTSEFAGHRVEMGATWVQGVVGSPVYALARDAGALGEEEGRGLPYERMDGFPDRVLTVAEGGEVVDADTVAGPIEELYRGMMEAARAGEAGGGGGVEEYLRRGLRAYQAARSAGGGGGGGKELEEVDEALLAMHINRERTDTSADDLGDLDLTAEGEYRDFPGEHVTIPGGYSRVVERLAAALPPGTVRLGLRLRRLKWGGTPVRLHFADGAPPLTADHVILTVSLGVLKASLGNKDTAGVGAAAIAFDPPLPPFKREAVARLGFGVVNKLFMEVEAVAPSEPEDVAGVQPAAAGFPFLHMAFRGHVSKIPWWMRGTESICPVHAGSTVALAWFAGREAAHLESLPDDDVIRGAHATLDSFLPAAPRWRVRRIKRSGWATDPLFLGSYSYVAVGSSGDDLDRMAEPLPRGPDAAADERPPSPRLLFAGEATHRTHYSTTHAAYLSGVREANRLLQHYRGGANHTT

Gene
PAO1
Protein
Polyamine oxidase 1
Organism
Arabidopsis thaliana
Length
472 amino acids
Function
Flavoenzyme involved in polyamine back-conversion (PubMed:16778015, PubMed:20532512, PubMed:21081665, PubMed:26973665). Catalyzes the oxidation of the secondary amino group of polyamines, such as spermine and its acetyl derivatives (PubMed:16778015, PubMed:20532512, PubMed:21081665). Substrate preference is thermospermine > norspermine > spermine > N(1)-acetylspermine (PubMed:16778015, PubMed:21081665). No activity detected when putrescine, spermidine or N(1)-acetylspermidine are used as substrates (PubMed:16778015). Plays an important role in the regulation of polyamine intracellular concentration (Probable) (PubMed:26973665). Involved in the production of hydrogen peroxide in response to salt and cold stresses (PubMed:26973665).
Similarity
Belongs to the flavin monoamine oxidase family.
Mass
52.866 kDa
Sequence
MSTASVIIIGAGISGISAAKVLVENGVEDVLILEATDRIGGRIHKQNFGDVPVELGAGWIAGVGGKESNPVWELASRFNLRTCFSDYTNARFNIYDRSGKIFPTGIASDSYKKAVDSAILKLKSLEAQCSGQVAEEAPSSPKTPIELAIDFILHDFEMAEVEPISTYVDFGEREFLVADERGYECLLYKMAEEFLVTSHGNILDYRLKLNQVVREVQQSRNGVVVKTEDGSVYEANYVIVSASIGVLQSDLLSFQPLLPRWKTEAIQKCDVMVYTKIFLKFPQCFWPCGPGQEFFIYAHEQRGYFTFWQHMENAYPGSNILVVTLTNEQSKRVEAQSDQETMKEAMSVLRDMFGATIPYATDILVPRWWNNRFQRGSYSNYPMISDNQLLQNIKAPVGRIFFTGEHTSEKFSGYVHGGYLAGIDTSKSLLEEMKQSLLLQPLLAFTESLTLTHQKPNNSQIYTNVKFISGTS