About Products Protein Database Contact

PAIP2

Gene
PAIP2
Protein
Polyadenylate-binding protein-interacting protein 2
Organism
Gallus gallus
Length
127 amino acids
Function
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).
Similarity
Belongs to the PAIP2 family.
Mass
15.043 kDa
Sequence
MKDPSRSSTSPSIISEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDSSSLEDLVVKSNLNPNAKEFVPGVKYLNI

Gene
PAIP2
Protein
Polyadenylate-binding protein-interacting protein 2
Organism
Homo sapiens
Length
127 amino acids
Function
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization.
Similarity
Belongs to the PAIP2 family.
Mass
14.984 kDa
Sequence
MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKYGNI

Gene
PAIP2
Protein
Polyadenylate-binding protein-interacting protein 2
Organism
Bos taurus
Length
124 amino acids
Function
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).
Similarity
Belongs to the PAIP2 family.
Mass
14.7 kDa
Sequence
MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY

Gene
Paip2
Protein
Polyadenylate-binding protein-interacting protein 2
Organism
Mus musculus
Length
124 amino acids
Function
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).
Similarity
Belongs to the PAIP2 family.
Mass
14.7 kDa
Sequence
MKDPSRSSTSPSIINDDVIINGHSHEEDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY

Gene
PAIP2
Protein
Polyadenylate-binding protein-interacting protein 2
Organism
Pongo abelii
Length
124 amino acids
Function
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).
Similarity
Belongs to the PAIP2 family.
Mass
14.744 kDa
Sequence
MKDPSRSSTSPSIINEDVIINGHSHEDDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNELVISDSSSLEDLVVKSNLNPNAKEFVPGVKY

Gene
Paip2
Protein
Polyadenylate-binding protein-interacting protein 2
Organism
Rattus norvegicus
Length
124 amino acids
Function
Acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. Its inhibitory activity on translation is mediated via its action on PABPC1. Displaces the interaction of PABPC1 with poly(A) RNA and competes with PAIP1 for binding to PABPC1. Its association with PABPC1 results in disruption of the cytoplasmic poly(A) RNP structure organization (By similarity).
Similarity
Belongs to the PAIP2 family.
Mass
14.7 kDa
Sequence
MKDPSRSSTSPSIINDDVIINGHSHEEDNPFAEYMWMENEEEFNRQIEEELWEEEFIERCFQEMLEEEEEHEWFIPARDLPQTMDQIQDQFNDLVISDGSSLEDLVVKSNLNPNAKEFVPGVKY