Protein
Neutral protease 2 homolog PADG_00776
Organism
Paracoccidioides brasiliensis (strain Pb18)
Function
Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine (By similarity).
Similarity
Belongs to the peptidase M35 family.
Sequence
MRRVSGILAVAAFTISAFAGVIQPVAKDARDSAELDVKLTQVDGTVIKAVVTNNGDKDLNILNLNFFRDTAPVKKVSIYSQGVEVPFGGIRVRHKTSDLSSDVITYLAPGESFEDEFDVAITSDLSQGGPVVLQTQGYVPTTDTGGKTLSGVVRYKSNKLEIDVDGTTAAKSFAAMNQFVKIAKLSSCEGSQGDDTRRALRDCASLSTLAAAQAWAGGPKMLEYFKANDDATRKLVADRFTAVALESSNLTGGSTTYYCRDPYNICTNNIIAYTIPAENLISNCPIYYTEFDNVNRKCHGQDRVTTSLHEFTHASSVFSPGTKDIAYGYNACILLSTRDALNNADTFALFAQSINAGC