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P23p89

Gene
P23p89
Protein
Major capsid protein
Organism
Thermus virus P23-45
Length
409 amino acids
Function
Assembles to form an icosahedric capsid shell with a T=7 symmetry although with a diameter of about 82 nm, which is a larger volume than the usual T=7 capsids (PubMed:30737287). A dramatic reconfiguration of the capsid shell that expands the procaspid from a diameter of 66 nm to a supersized capsid of 82 nm, allows packaging of the large viral DNA genome (PubMed:30737287). The capsid decoration protein binds the expanded capsid and stabilizes it (PubMed:30737287).
Similarity
Belongs to the lambda phage major capsid protein family.
Mass
46.63 kDa
Sequence
MRVPININNALARVRDPLSIGGLKFPTTKEIQEAVAAIADKFNQENDLVDRFFPEDSTFASELELYLLRTQDAEQTGMTFVHQVGSTSLPVEARVAKVDLAKATWSPLAFKESRVWDEKEILYLGRLADEVQAGVINEQIAESLTWLMARMRNRRRWLTWQVMRTGRITIQPNDPYNPNGLKYVIDYGVTDIELPLPQKFDAKDGNGNSAVDPIQYFRDLIKAATYFPDRRPVAIIVGPGFDEVLADNTFVQKYVEYEKGWVVGQNTVQPPREVYRQAALDIFKRYTGLEVMVYDKTYRDQDGSVKYWIPVGELIVLNQSTGPVGRFVYTAHVAGQRNGKVVYATGPYLTVKDHLQDDPPYYAIIAGFHGLPQLSGYNTEDFSFHRFKWLKYANNVQSYLPPFPPKVEL