olfml3

Olfactomedin-like protein 3

416 amino acids

Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid protease BMP1 and its substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation by BMP1 (By similarity).

Belongs to the OLFML3 family.

47.756 kDa

MAGIVACILLVFVTVITAQQQAVFLEYIQGRMGVLEERLSQWHDQSSRYSGELRDFKNQVLKMLENIEKERESLRNEMENTNVRVDRLEREVDYIETQNPAPPCVEIDEKLTELHDAKKKKKEKYEKITGCPAADIPGKEETDEILIPPVIRKPYCSDTISQVTAMKILKRFGSSAGLWTKDLAGNSDRIYVFDGAGNDTVYVYPRMKEFTLSSSTRKAAKIKLPFPWIGTGHIVYDGNLYYIRQDNEFQVIKFNLANKTIIDSAVLPIEQQVPVYGLSKFNYIDIVADEEGLWVIYATKENEKNICLAKLDPSSLSIEQMWDTPCPIENAESAFVVCGSLYVVYNTKLPSRSRIQCVFDVSGTISSENVPIVYFPKRYGSHSSMKYNPKEKQIYAWDDGYQMLYKLNMKHRDELY

OLFML3

Olfactomedin-like protein 3

406 amino acids

Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes (By similarity).

Belongs to the OLFML3 family.

45.886 kDa

MGPHTQLLILLLLSWLGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEVDEKVTGGPGTKGKGRRNEKYDMITDCGYTISQVRSMKILKRFGGPAGLWTKDPLGPAEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYYARRPPGGPGGGGELQNTLQLIKFHLANRTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV

OLFML3

Olfactomedin-like protein 3

406 amino acids

Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes.

Belongs to the OLFML3 family.

46.01 kDa

MGPSTPLLILFLLSWSGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEVAEKEREALRTEADTISGRVDRLEREVDYLETQNPALPCVEFDEKVTGGPGTKGKGRRNEKYDMVTDCGYTISQVRSMKILKRFGGPAGLWTKDPLGQTEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRVRVPFPWVGTGQLVYGGFLYFARRPPGRPGGGGEMENTLQLIKFHLANRTVVDSSVFPAEGLIPPYGLTADTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALPYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMRKKEEEV

Olfml3

Olfactomedin-like protein 3

406 amino acids

Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes (By similarity).

Belongs to the OLFML3 family.

45.746 kDa

MGPSAPLLLLFFLSWTGPLQGQQHHLVEYMERRLAALEERLAQCQDQSSRLAAELRDFKNKMLPLLEVAEKERETLRTEADSISGRVDRLEREVDYLETQNPALPCVELDEKVTGGPGAKGKGRRNEKYDMVTDCSYTVAQVRSMKILKRFGGSAGLWTKDPLGPAEKIYVLDGTQNDTAFVFPRLRDFTLAMAARKASRIRVPFPWVGTGQLVYGGFLYYARRPPGGPGGGGELENTLQLIKFHLANRTVVDSSVFPAESLIPPYGLTADTYIDLAADEEGLWAVYATRDDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLAPERAALSYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMKKKEEEV

Olfml3

Olfactomedin-like protein 3

406 amino acids

Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity). May have matrix-related function involved in placental and embryonic development, or play a similar role in other physiological processes (By similarity).

Belongs to the OLFML3 family.

45.961 kDa

MGPSAPLLLFFLLSWPGSLQGQQHHLVEYMERRLAALEERLAQCQDQSSRHAAELRDFKNKMLPLLEVAEKERETLRTEADSISGRVDRLEREVDYLETQNPALPCVELDEKVTGGPGTKGKGRRNEKYDMVTDCSYTISQVRSMKILKRFGGSAGLWTKDPLGPAEKIYVLDGTQNDTAFVFPRLRDFTLTMAARKASRIRVPFPWVGTGQLVYGGFLYYARRPPGGAGGGGELENTLQLIKFHLANRTVVDSSVFPAERLIPPYGLTVDTYIDLAADEEGLWAVYATREDDRHLCLAKLDPQTLDTEQQWDTPCPRENAEAAFVICGTLYVVYNTRPASRARIQCSFDASGTLTPERAALSYFPRRYGAHASLRYNPRERQLYAWDDGYQIVYKLEMKKKEEEV

OLFML3

Olfactomedin-like protein 3

392 amino acids

Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid proteases and their substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation (By similarity).

Belongs to the OLFML3 family.

44.846 kDa

MGPWRCLLLLPLLAAAPRAQQQQFMEYVERRLALLEERIAQWHDQSSRYSTELRDFKNQVLGMLETAEKEREALRAEAEGAAARVDRLEREVDYLETQNPAPPCVEVDEVLMEKQAATAKQRKNEKYTKLTDCSDTIASVRAMKILKRFGSSAGLWTKDAAGSSEKIYVFDGTANDTVYIFPRMREFTLFSATRRAARIKLPYPWVGTGHLVYGGYLYYIRQQGPFQVIKFDLANKTVVDSSVFPAEEQIPVFGLSPFTYIELAADEEGLWAIYATKENEKNICLAKLDPDSLDIEQMWDTPCPRENAEGAFVVCGALHVAYNTRLPSRSRVQCVFDVSGTLPPEEASLVYFPKRYGSHSSMKYSPRERQVYAWDDGYQIIYRMEMKKKLEV

olfml3

Olfactomedin-like protein 3

392 amino acids

Secreted scaffold protein that plays an essential role in dorsoventral patterning during early development. Stabilizes axial formation by restricting chordin (CHRD) activity on the dorsal side. Acts by facilitating the association between the tolloid protease BMP1 and its substrate chordin (CHRD), leading to enhance chordin (CHRD) degradation by BMP1.

Belongs to the OLFML3 family.

45.11 kDa

MMAGIVACILLVFVTVITAQPQAVFLEYIQGRMGVLEERIAQWHDQSSRFSGELRDFKNQVLKMLENIEKERDSLRNEMENTNVRVNRLEREVDYIETQNPAPPCVEIDEKLSDHHGAKKKKKEKYQKITDCSDTISQVTAMKILKRFGSSAGLWTKDLAGNSDRIYVFDGAGNDTVYMYPRMKEFTLSSPTRKAAKIRLPFPWIGTGHIVYDGNLYYIRQDNEFQVIKFSLANKTIIDSAVLPIEQQVPVYGLSKFNYIDIVADEEGLWVIYATKENEKNICLAKLDPSSLSIEQMWDTPCPIENAESAFVVCGSLYVVYNTKLPSRSRIQCVFDVSGTISSENVPIVYFPKRYGSHSSMKYNPREKQIYAWDDGYQIIYKLNMKHRDELY