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NUDT12

Gene
NUDT12
Protein
Peroxisomal NADH pyrophosphatase NUDT12
Organism
Homo sapiens
Length
462 amino acids
Function
Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle.
Similarity
Belongs to the Nudix hydrolase family. NudC subfamily.
Mass
52.076 kDa
Sequence
MSSVKRSLKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENYFSKTLLDRKSEKRNNSDWLLAKESHPATVFILFSDLNPLVTLGGNKESFQQPEVRLCQLNYTDIKDYLAQPEKITLIFLGVELEIKDKLLNYAGEVPREEEDGLVAWFALGIDPIAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNATKIEEGGYKRLCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVACQPWPMPSSLMIGCLALAVSTEIKVDKNEIEDARWFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
Protein
Peroxisomal NADH pyrophosphatase NUDT12: NUDT12

Gene
NUDT12
Protein
Peroxisomal NADH pyrophosphatase NUDT12
Organism
Macaca fascicularis
Length
462 amino acids
Function
Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle (By similarity).
Similarity
Belongs to the Nudix hydrolase family. NudC subfamily.
Mass
52.092 kDa
Sequence
MSSVKRSPKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENYFSKTLLDRKSEKRNNADWLLAKESHPATVFILFSDLNPLVTLGGNKESFQQPEVRLCQLNYKDIKDYLAQPEEITLIFLGVELEMKDKLLNYAGEVPREEEDGLVAWFALGIDPIAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNGTKIEEGGYKRVCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTRCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVSCQPWPMPSSLMIGCLAVAVSTEIKVDKNEIEDARWFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
Protein
Peroxisomal NADH pyrophosphatase NUDT12: NUDT12

Gene
Nudt12
Protein
Peroxisomal NADH pyrophosphatase NUDT12
Organism
Mus musculus
Length
462 amino acids
Function
Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle (By similarity).
Similarity
Belongs to the Nudix hydrolase family. NudC subfamily.
Mass
51.511 kDa
Sequence
MSSVKRNPKKEMISELHSSAAEGNVAKLAGILSHSPSLLNETSENGWTALMYAARNGHPDVVQFLLEKGCDRSLVNKARQTALDIAAFWGYRHIANLLANAKGGKKPWFLTNEVDECENYFSRTLLDRRSDKRNNSDWLQAKESHPTTVYLLFSDLNPLVTLGGNKESSQQPEVRLCQLNYPDVKGYLAQPEKITLVFLGVELEMRKGSPAQAGGVPEEEEDGLVAWFALGIEPGAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGSATKIEEGGYKRVCVRETCPSLQGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVSCQPWPMPSSLMIGCLAVAVSTEIKVDKNEIEDARWFTREQVVDVLTKGKQQAFFVPPSRAIAHQLIKHWVGMNPNL
Protein
Peroxisomal NADH pyrophosphatase NUDT12: Nudt12

Gene
NUDT12
Protein
Peroxisomal NADH pyrophosphatase NUDT12
Organism
Pongo abelii
Length
462 amino acids
Function
Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle (By similarity).
Similarity
Belongs to the Nudix hydrolase family. NudC subfamily.
Mass
52.1 kDa
Sequence
MSSVKRTPKQEIVTQFHCSAAEGDIAKLTGILSHSPSLLNETSENGWTALMYAARNGHPEIVQFLLEKGCDRSIVNKSRQTALDIAVFWGYKHIANLLATAKGGKKPWFLTNEVEECENYFSKTLLDRKSEKRNNSDWLLAKESHPATVFILFSNLNPLVTLGGNKESFQQPEVRLCQLNYTDIKDYLAQPEKITLIFLGVELEIKDKLFNYAGEVPREEEDGLVAWFALGIDPIAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWYSRYKFCPTCGNATKIEEGGYKRVCLKEDCPSLNGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVACQPWPMPSSLMIGCLALAVSTEIKVDKNEIEDAHWFTREQVLDVLTKGKQQAFFVPPSRAIAHQLIKHWIRINPNL
Protein
Peroxisomal NADH pyrophosphatase NUDT12: NUDT12

Gene
NUDT12
Protein
Peroxisomal NADH pyrophosphatase NUDT12
Organism
Bos taurus
Length
444 amino acids
Function
Hydrolyzes NAD(P)H to NMNH and AMP (2',5'-ADP), and diadenosine diphosphate to AMP. Has also activity towards NAD(P)(+), ADP-ribose and diadenosine triphosphate. May act to regulate the concentration of peroxisomal nicotinamide nucleotide cofactors required for oxidative metabolism in this organelle (By similarity).
Similarity
Belongs to the Nudix hydrolase family. NudC subfamily.
Mass
50.119 kDa
Sequence
MSSVKRSLNQEIISQFHYSAAEGDIAKLTAILSHSPSLLNETSENGWSALICDRSIVNKSRQTALDIAKFWGYKHIANLLANAKGGKKPWFLTNEVEECENYFSKTLLDRKSEKRNNSDWLLAKESHPATVYILFSDLNPLVTLGGNKESFQQPEVRLCQLNYTDIKDYLAQPEKITLIFLGVELEMKKEFFNYAGEISKEEEDGLVAWFALGIDTVAAEEFKQRHENCYFLHPPMPALLQLKEKEAGVVAQARSVLAWHSRYKFCPTCGNATKIEEGGYKRVCLKEDCPSLHGVHNTSYPRVDPVVIMQVIHPDGTKCLLGRQKRFPPGMFTCLAGFIEPGETIEDAVRREVEEESGVKVGHVQYVSCQPWPMPSSLMIGCLAVAVSTEIKVDKNEIEDARWFTREQVVDVLTKGKQQAFFVPPSRAIAHQLIKHWIGMNPNL
Protein
Peroxisomal NADH pyrophosphatase NUDT12: NUDT12

Gene
NUDT12
Protein
Nudix hydrolase 12, mitochondrial
Organism
Arabidopsis thaliana
Length
203 amino acids
Function
Probably mediates the hydrolysis of some nucleoside diphosphate derivatives.
Similarity
Belongs to the Nudix hydrolase family.
Mass
23.869 kDa
Sequence
MSVLSSRTGRDRQRYDNNFRLVSGCIPYRLMKADETEEDSGVDFVNKLEVLMVSSPNRHDLVFPKGGWEDDETVLEAASREAIEEAGVKGILRELPLGVWEFRSKSSTVEDECLGGCKGYMFALKVTEELEDWPERKNRERRWLTVKEALELCRYEWMQRALEEFLRVMEDERRLRTEEETVHDSSKLEEESQIDPWYCFVVN
Protein
Nudix hydrolase 12, mitochondrial: NUDT12