NTH1

Neutral trehalase

754 amino acids

Belongs to the glycosyl hydrolase 37 family.

86.92 kDa

MDGKVNNNPPRSRHRRTSSLEEVVDPFSTPDVYYGPKSDPSKLLSKNRFTRTRTFSVAEPGGGKGHSSSYTSPYFDTTVPLRRRGSEDDSYSASQGQRRFYIEDVDKTLKELLASEDTDGNYQITIEDTGPKVIRVGTVNSNGYKHVHIRGTYMLSNLLQELTLAKLFNRKQVILDEARLNENPVNRMTRLISGQFWKSLTRRIDSNNIAKIAYDTKIDTPKAKNPRIYVPYNCQDEYQQLVQWSEMDPSLQLEVNYLPKDITPEFVKSLNDKPGLLCLAMESHMDPVTGEETWVGFPYAVPGGRFNELYGWDSYFMALGLLESNKLDVARGMVEHFIFEIDHYGKILNANRSYYLCRSQPPFLTDMALQVCRKMGGDKNPVAVDLLRRAFKAAIKEYLTVWTASPRLDEKTGLSCYHPDGIGIPPETEPGHFDSILRKYAEKYNVSIPEFRDLYNSQKVHEPDLDVFFLHDRGVRESGHDTTYRFENVCAYLATIDLNSLLYKYEVDIAYVIKKYFGDNFEGLPEGHRTSNDWEKLAEVRKERIDKYLWDEETGFYYDYNVKTEKRTSYESVTTFWALWAGMSSQEQAQRMVENALPKLEEFGGLVACTARSRGELSLDRPTRQWDYPFGWAPHQILVWDGLVRYGYENHTRRLAYRWLFLMTKAFVDYNGIVVEKYDVTRGTDPHRVDAEYGNQGADFKGVATEGFGWVNSSYLLGMKYMNNFARRALGTCVTPKVFFGRLPPKEKKKYGLE

NTH1

Neutral trehalase

751 amino acids

Belongs to the glycosyl hydrolase 37 family.

85.879 kDa

MSQVNTSQGPVAQGRQRRLSSLSEFNDPFSNAEVYYGPPTDPRKQKQAKPAKINRTRTMSVFDNVSPFKKTGFGKLQQTRRGSEDDTYSSSQGNRRFFIEDVDKTLNELLAAEDTDKNYQITIEDTGPKVLKVGTANSYGYKHINIRGTYMLSNLLQELTIAKSFGRHQIFLDEARINENPVNRLSRLINTQFWNSLTRRVDLNNVGEIAKDTKIDTPGAKNPRIYVPYDCPEQYEFYVQASQMHPSLKLEVEYLPKKITAEYVKSVNDTPGLLALAMEEHFNPSTGEKTLIGYPYAVPGGRFNELYGWDSYMMALGLLEANKTDVARGMVEHFIFEINHYGKILNANRSYYLCRSQPPFLTEMALVVFKKLGGRSNPDAVDLLKRAFQASIKEYKTVWTASPRLDPETGLSRYHPNGLGIPPETESDHFDTVLLPYASKHGVTLDEFKQLYNDGKIKEPKLDEFFLHDRGVRESGHDTTYRFEGVCAYLATIDLNSLLYKYEIDIADFIKEFCDDKYEDPLDHSITTSAMWKEMAKIRQEKITKYMWDDESGFFFDYNTKIKHRTSYESATTFWALWAGLATKEQAQKMVEKALPKLEMLGGLAACTERSRGPISISRPIRQWDYPFGWAPHQILAWEGLRSYGYLTVTNRLAYRWLFMMTKAFVDYNGIVVEKYDVTRGTDPHRVEAEYGNQGADFKGAATEGFGWVNASYILGLKYMNSHARRALGACIPPISFFSSLRPQERNLYGL

NTH1

Neutral trehalase

736 amino acids

Plays a role in pathogenicity, specifically in proliferation of invasive hyphae in rice blast disease.

Belongs to the glycosyl hydrolase 37 family.

84.603 kDa

MSEAPQARRVGSVDDHSVYDDAKTYYTSEERHNNSRSGPRQRTYSQNSLLGQMERLGLKEPFRRGSHDESNHNRRFLIQVDPTLESLKSQEDTDGNMQITIEDNGPKVLTLRTAGSNGHNRFDIRGTYMLSNLLQELTLAQEYGRKQVILDEARLNENPVNRLSRLIRDHFWDALTRRIDASSIEVAAKDPKDWTDDPRPRIYVPKGAPEQLEYYKKLAADKPDIRLDVVELPETITPEYVVGINKAPGLLAVDMEETVDPKTGERVMSGRPFVVPGGRFNELYGWDSYMESLGLLVNDKVYLAKSMVLNFCFCIKHYGKILNATRSYYLCRSQPPFLTDMALRVYDKIRHEPDATEFLRTAILAAIKEYHSVWVAEPRLDPVTGLSRYRPEGTGVPPETEADHFLHILEPYYKKHNMTFKEFVEAYNFGRIREPELDKYFLHDRAVRESGHDTSYRLEGVCADLATVDLNTLLFKYETDIARTIRNVFGDKLVIPAEYCVGSLQPGQVETSAIWDRRSKRRKLAIDKYLWNEEAGMYFDYDTAKRQQCNYESCTTFWALWAGVASPKQAAIMVTRALPKFEAYGGLLSGTEESRGQIGLDRPNRQWDYPYGWAPQQMLAWTGLYRYSFTEEAERLAYKWLFMITKAFSDFNGVVVEKYDVTRPVDPHRVDAEYGNQGLGFKGVAKEGFGWVNASYIYGLQIINAHMRRALGTLTPYDTFIKALEDNRNRALSEMV

nth1

Endonuclease III homolog

443 amino acids

Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.

Belongs to the Nth/MutY family.

48.637 kDa

MCIEAMRTSRASRETAKVLQALSPPARRQTRSTSHSALLKGFAYNAGKTEADPDDGEDDGSSLTSVDTVDIEDILEPSAKRRKTKASSAAKTTSNSTRRTPEKKVEKLVKKENSQPKARRVPARKVKNEDGSFTVEAPSNWDAIYSIVKKMREDNPTAPVDTMGCAELYWRASSPRDRRFQTLIALMLSSQTKDTVTAVAMQRLHTELGEGGAPAIKLETEHAESIVKQEAENGEPAIKQEAKDGVPPANPSHDSTLNLENILAVSPERLNSLIGTVGFHNNKTKYIKKAAEIIRDQYNSDIPSTPAELMKLPGVGPKMAYLCMSAAWGKHEGIGVDVHVHRITNLWGWHKTKTPEETRMSLESWLPKDKWHEINKLLVGLGQTVCLPVGRRCGDCGLAGTKLCKSEIKGMAPKNNGRGLPKKEIVVETFSLTGEPKIKVEGE

NTH1

Endonuclease III homolog 1, chloroplastic

379 amino acids

Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.

Belongs to the Nth/MutY family.

41.728 kDa

MILLVNGGAATSIHPNAARFYRIGTMSRQIHGAVSSSKHISLKTQHPLSDSNSELAYGASGSETRVYTRKKRLKQEPFEPLEKYSGKGVNTHKLCGLPDIEDFAYKKTIGSPSSSRSTETSITVTSVKTAGYPPENWVEVLEGIRQMRSSEDAPVDSMGCDKAGSFLPPTERRFAVLLGALLSSQTKDQVNNAAIHRLHQNGLLTPEAVDKADESTIKELIYPVGFYTRKATYMKKIARICLVKYDGDIPSSLDDLLSLPGIGPKMAHLILHIAWNDVQGICVDTHVHRICNRLGWVSRPGTKQKTTSPEETRVALQQWLPKEEWVAINPLLVGFGQMICTPIRPRCEACSVSKLCPAAFKETSSPSSKLKKSNRSKEP

nth1

Endonuclease III homolog

355 amino acids

Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. Has also 8-oxo-7,8-dihydroguanine (8-oxoG) DNA glycosylase activity. Also involved in the repair of 7-methylguanine lesions, although it cannot directly repair alkylated DNA bases. Probably does so via excision of methylformamidopyrimidine (mFapy) lesions, a spontaneous processing product of 7-methylguanine.

Belongs to the Nth/MutY family.

40.227 kDa

MSKDYGTPPENWREVYDEICKMKAKVVAPVDVQGCHTLGERNDPKKFRFQTLVALMLSSQTKDIVLGPTMRNLKEKLAGGLCLEDIQNIDEVSLNKLIEKVGFHNRKTIYLKQMARILSEKFQGDIPDTVEDLMTLPGVGPKMGYLCMSIAWNKTVGIGVDVHVHRICNLLHWCNTKTEEQTRAALQSWLPKELWFELNHTLVGFGQTICLPRGRRCDMCTLSSKGLCPSAFKEKSGITITKRKVKTIKRVKKRPASESPPLSPLSLPTDDLYYQSIEDKSLIKLEDLDPVDSISHMNEPLKKEPAADIDVDQKPPVAFHSTTKETRSLRRSKRVAKKSSQYFSQQSLQDIEDLV

NTH1

Endonuclease III homolog

238 amino acids

Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines.

Belongs to the Nth/MutY family.

26.755 kDa

MGSASGEEREGPLGLYLEIKMQRKDIVSPVDTMGCSITPSCRTEEERRFHILVSLLLSSQTKDEVTYEAMARLRKLLPESAATDGEARGGLTIERVANSDVKHINECIKKVGFHNRKAANLKKIAEILREKGLPREMKDLISLPGIGNKMALLYMSHACNRTVGISVDTHVHRISNRIGLVRTRDVESTRRELERVVPRKEWKTINNILVGFGQTICVAKRPRCEECCIRGRCPSSLF