NFRKB

Nuclear factor related to kappa-B-binding protein

1299 amino acids

Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex.

Belongs to the NFRKB family.

139.001 kDa

MDSLDHMLTDPLELGPCGDGHGTRIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQFLPQFPEDSAEQQNELILALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLNSQQQYFHRLLKQILASRSDLLEMARRSGPALPFRQKRPSPSRTPEEREWRTQQRYLKVLREVKEECGDTALSSDEEDLSSWLPSSPARSPSPAVPLRVVPTLSTTDMKTADKVELGDSDLKIMLKKHHEKRKHQPDHPDLLTGDLTLNDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEEKKKKKIKTIKSEAEDLAEPLSSTEGVAPLSQAPSPLAIPAIKEEPLEDLKPCLGINEISSSFFSLLLEILLLESQASLPMLEERVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFQLWLETKDQAFCKQENEDSSDATTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSSKESSIKVLSSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPAIPISPPPVSAVNKSGPSTVSEPAKSSSGVLLVSSPTMPHLGTMLSPASSQTAPSSQAAARVVSHSGSAGLSQVRVVAQPSLPAVPQQSGGPAQTLPQMPAGPQIRVPATATQTKVVPQTVMATVPVKAQTTAATVQRPGPGQTGLTVTSLPATASPVSKPATSSPGTSAPSASTAAVIQNVTGQNIIKQVAITGQLGVKPQTGNSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGTGGNTTGKGISATLHVTSNPVHAADSPAKASSASAPSSTPTGTTVVKVTPDLKPTEASSSAFRLMPALGVSVADQKGKSTVASSEAKPAATIRIVQGLGVMPPKAGQTITVATHAKQGASVASGSGTVHTSAVSLPSMNAAVSKTVAVASGAASTPISISTGAPTVRQVPVSTTVVSTSQAGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ

Nfrkb

Nuclear factor related to kappa-B-binding protein

1296 amino acids

Putative regulatory component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Modulates the deubiquitinase activity of UCHL5 in the INO80 complex (By similarity).

Belongs to the NFRKB family.

138.764 kDa

MDSLDHMLTDPLELGPCGDGHSTGIMEDCLLGGTRVSLPEDLLEDPEIFFDVVSLSTWQEVLSDSQREHLQQFLPRFPADSVEQQRELILALFSGENFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCFKSQYKRYLNSQQQYFHRLLKQILASRSDLLEMARRSGPALPFPHKHHSPSRSPEEREWRTQQRYLKVLREVKEECGDTALSSDEEDLSSWLPSSPARSPSPAVPLRVVPTLSTTDMKTADKIELGDSDLKLMLKKHHEKRKHQPDHPDLLTGDLTLSDIMTRVNAGRKGSLAALYDLAVLKKKVKEKEEKKKKKIKLIKSEAEDLAEPLSSTEGVPTLSQAPSPLAISSIKEEPLEDIKPCLGINEISSSFFSLLLEILLLESQASLPMLEDRVLDWQSSPASSLNSWFSAAPNWAELVLPALQYLAGESRAVPSSFSPFVEFKEKTQQWKLLGQSQDNEKELAALFHLWLETKDQAFCKENEDSSDAMTPVPRVRTDYVVRPSTGEEKRVFQEQERYRYSQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSTQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKARKALQQKPKPPSKVKSSNKEGSTKGLSGPSEQSQMSLSDSSMPPTPVTPVTPTTPALPTPISPPPVSAVNRSGSSTVSEPAQSSSGVLLVSSPTMPQLGTMLSPASIQTPPSSQATARVVSHSSSAGLPQVRVVAQPSLPAVSQQSVGPAQPLPQMPAGPQIRVPVTATQTKVVPQAVMATVPVKGQTAAASVQRPGPGQTGLTVTNLPAAVSPVSKTAMSSPGNSAPSASTTAVIQNVTGQNIIKQVSITGQLGVKPQTGSSIPLTATNFRIQGKDVLRLPPSSITTDAKGQTVLRITPDMMATLAKSQVTTVKLTQDLFGAGSGTAGKGISATLHVTSNPVHAADSPAKAPSASVPSSAPAGTTVVKVTPDLKPTETANSAFRLMPALGVSVADQKGKNTVASSEAKPAATIRIVQGLGVMPPKAGQTITVAAHAKQGASVAGGSGTVHSSTVSLPSINAAVSKTVAVASGATSTPISIGTGAPTVRQVPVNTTVVSTSQSGKLPTRITVPLSVISQPMKGKSVVTAPIIKGNLGANLSGLGRNIILTTMPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLQQGTASGSSKAVSTVVVTTAPSPKQAPEQQ

nfrkb

Nuclear factor related to kappa-B-binding protein

1265 amino acids

Binds to DNA.

Belongs to the NFRKB family.

137.075 kDa

MESLDSMLTDPLELGPCVESNGTGIMEECMLGGTRVSLPEDLLEDPDLFFEVVSRDTWKNVLSDSQREHLKQFLPVFPDDNANQQEKIIQSLFRGDNFRFGNPLHIAQKLFRDGHFNPEVVKYRQLCLKSQYKRYLTSQQQYFHKLLKQILASRKELLDLARKNGPDQVLKKKPSSLRNTPEERETRAQCRYLKILREVKDECGDGTLSSEEEDLSSWLPESPTHCPSVAVPLRVIPTLSTQDMKTADKQEFTNHDLKLLLRRHREKRKRQSDHPDLITDNLSMNDIMTRVNAGRKGSLAALFDLATMKKRVKEKDDKKKKKLKTIKTEVEDYPDMPDEADIMPAVLPPETPQVTLTAVKEEPLEDVKPPLPFNEISACFFCLLLDILTMEGPCSLPLLEDKVSDWQSLPASTLNSWFSVAPNWCDLVHPALIYLSGECKVASSSFTPFVEFREKTQQWKCVVSSSDSEKELVAHFHLWLETKDQIYSKENEDCIDASTPIPRVRTDYIVRPSSGEEKHVFQEQERHRYIQPHKAFTFRMHGFESVVGPVKGVFDKETSLNKAREHSLLRSDRPAYVTILSLVRDAAARLPNGEGTRAEICELLKDSQFLAPDVTSAQVNTVVSGALDRLHYEKDPCVKYDIGRKLWIYLHRDRSEEEFERIHQAQAAAAKAKKALQQKPKPPTKMKSGSKECSLKLCGTPEPAQLSLTESSMPPTPGTPGTPTPPALPSTPMSPSTSATVNKIVASTITETQKSSQSVLLVSSPAMPQLSTLLSPAVTSQSTSVTPTSGRAATISSSTGVPQVRIVTATTGVPTTQSAAVVTQPLSPVISHIRLPVTTTPTKALAQTQVVTVPVKNQTTIGASRLGASVTTQGSVTVNTLNSSAGLASKSVVSSPGASGPAILQSITGQSIIKQVALSGQLGVKSQPSSSLPLSSTNFRIQGKDVLRLPPSSITTDAKGQTILRITPDMMATLAKSQVTAVKLSQELFSAAPVSTTGKGLLHVTSSPSSPSPPAPSTIKLTPEMKPAETSSSSFRLMPALGISVAEQKGKVVTAGESKPATTIRIVQGLGVMPPKVSATQSITVSAKPVTVPSSTIVNPVHSASNVSLPTVNSTAVKTAPTGIVVGTGAATVRQIPVTTTQQGKLPARITVPLSVLSQPMKGKGVVTAPIIKGNLGANISGLGRNIILTTVPAGTKLIAGNKPVSFLTAQQLQQLQQQGQATQVRIQTVPASHLPQGTSPASSKAVSTVVVTTTPTTKPTQEPQ