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NEQ515

Gene
NEQ515
Protein
N-glycosylase/DNA lyase
Organism
Nanoarchaeum equitans (strain Kin4-M)
Length
216 amino acids
Function
DNA repair enzyme that is part of the base excision repair (BER) pathway; protects from oxidative damage by removing the major product of DNA oxidation, 8-oxoguanine (GO), from single- and double-stranded DNA substrates.
Similarity
Belongs to the archaeal N-glycosylase/DNA lyase (AGOG) family.
Mass
26.005 kDa
Sequence
MEDPLIKILKQFSIEDAKYVEYNLDRQFLALKENPKPVGLVIANALISYQLTMPGERYWELFAKKVNSFNDLYDFVKKYNPRFLSNKLKRLERFKPYIDIIEQNREHYYENMVALNKFLAKIMNQNIYDKTIVFSIKMFAYAMRALGYKFKPFPFEIAIPLDYRLKKINPDLNYWFYVSKQTNIPPLHIDSLIWPIFRIKNLPKKFALLKEYLSNL