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NDRG2

Gene
NDRG2
Protein
Protein NDRG2
Organism
Homo sapiens
Length
371 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation.
Similarity
Belongs to the NDRG family.
Mass
40.798 kDa
Sequence
MAELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC

Gene
Ndrg2
Protein
Protein NDRG2
Organism
Mus musculus
Length
371 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity).
Similarity
Belongs to the NDRG family.
Mass
40.789 kDa
Sequence
MAELQEVQITEEKPLLPGQTPETAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAIFTYHDVGLNYKSCFQPLFRFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCILQYLNFSTIIGVGVGAGAYILSRYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPDMILGHLFSQEELSGNSELIQKYRGIIQHAPNLENIELYWNSYNNRRDLNFERGGETTLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASIDGSRSRSRTLSQSSESGTLPSGPPGHTMEVSC

Gene
NDRG2
Protein
Protein NDRG2
Organism
Pongo abelii
Length
371 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity).
Similarity
Belongs to the NDRG family.
Mass
40.77 kDa
Sequence
MAELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC

Gene
Ndrg2
Protein
Protein NDRG2
Organism
Rattus norvegicus
Length
371 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor (By similarity). May be involved in dendritic cell and neuron differentiation.
Similarity
Belongs to the NDRG family.
Mass
40.779 kDa
Sequence
MAELQEVQITEEKPLLPGQTPEAAKEAELAARILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAIFTYHDVGLNYKSCFQPLFQFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSQDQLADMIPCILQYLNFSTIIGVGVGAGAYILSRYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRSLITHAPNLENIELYWNSYNNRRDLNFERGGEMTLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFVQGMGYMASSCMTRLSRSRTASLTSAASIDGSRSRSRTLSQSSESGTLPSGPPGHTMEVSC

Gene
ndrg2
Protein
Protein NDRG2
Organism
Danio rerio
Length
368 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation (By similarity).
Similarity
Belongs to the NDRG family.
Mass
40.468 kDa
Sequence
MTTEMQEIAITEEKPLLPGQSDAVKDAEIAARILLDQGQEHTVETPHGVLHVTVHGSGNARRPAILTIHDVGMDSKSCFSTLFRFEEMQEIVKNFTVVHIDAPGQEEGAAVYPAGYQYASMDQVSEMLPAVLQFFNFRTIIGVGVGAGAYILSRFTLNNPEAVEGLVLVNVDPNARGWMDWAAHKLSNLTSSLSDQIISHLFSQQELSANTELIQTHRERITKAPNLLNIELFWKSYLGRRDLSLDRNNTFKCPVMLVVGDQAPYEEAAVECNSKLDPTTTSFLKMADAGGMPQLTQPSKLTEAFKYFIQGMGYMASSCMTRLSRSRTTSLSSSYSMEGSRSRSRTLSQGSQGGQLPPSPSNTMEVSC

Gene
ndrg2
Protein
Protein NDRG2
Organism
Xenopus laevis
Length
360 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation (By similarity).
Similarity
Belongs to the NDRG family.
Mass
39.386 kDa
Sequence
MSELHEVQITEDNPLLQDPLKAAELAAKLLQVQEQKHSIETPYGVVTVTIQGTPKPKRPAIVTFHDVGMDHKMCFDTLFKYEDMCEIVKNFVVCHIDAPGQEDGATIYPPGYQYPSLDQLAETIPCVLQYLNFPSIIGIGVGAGAYIFAKYTLSHANTVEGLVLINIDPNAKGWMDWAAQKLTGLTQSISDKMLGHLFSAEEISGNSDVVRQYKASISNSPLISNYQLYWNSYNSRRDLNFERGGGVTLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQITQPGKMTEAFKYFVQGMGYMASSVMTRLSRSRTASLSSEGNRSRSRTLSQSSESGGGPPAPLAEVTC

Gene
ndrg2
Protein
Protein NDRG2
Organism
Xenopus tropicalis
Length
360 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes. May be involved in neuron differentiation (By similarity).
Similarity
Belongs to the NDRG family.
Mass
39.344 kDa
Sequence
MSELQEVQITEDNPLLQDPLKAAELAAKLLQVQEQKHSIETPYGVVTVTIQGTPKPKRPAIVTFHDVGMDHKMCFDTLFKYEDMCEIVKNFVVCHIDAPGQEEGSAVYPPGYQYPSLDQLAETIPCVLQYLNFPSIIGIGVGAGAYIFAKYTLSHANTVEGLVLINIDPNAKGWMDWAAQKLTGLTQSISDMMLGHLFSAEELSGNSDVVRQYKASILNSPLISNYQLYWNSYNSRRDLNLERGGGVTLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQITQPGKLTEAFKYFVQGMGYMASSCMTRLSRSRTASLSSEGNRSRSRTLSQSSESGGGPPAPLAEVTC

Gene
NDRG2
Protein
Protein NDRG2
Organism
Bos taurus
Length
357 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity).
Similarity
Belongs to the NDRG family.
Mass
39.208 kDa
Sequence
MAELREVQITEEKPLLPGQTPEVAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFADMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCILQYLNFSTIIGIGVGAGAYVLSRYALTHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSISEMILGHLFSQEELSGNSELIQKYRNIIAHAPNLDNIELYWNSYNNRRDLNFVRGGDTTLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASIDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC

Gene
NDRG2
Protein
Protein NDRG2
Organism
Macaca fascicularis
Length
357 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity).
Similarity
Belongs to the NDRG family.
Mass
39.157 kDa
Sequence
MAELQEVQITEEKPLLPGQTPEAAKIHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFGDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTVIGVGVGAGAYILSRYALNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSSLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASIDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC

Gene
NDRG2
Protein
Protein NDRG2
Organism
Pan troglodytes
Length
357 amino acids
Function
Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation (By similarity).
Similarity
Belongs to the NDRG family.
Mass
39.361 kDa
Sequence
MAELQEVQITEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGVGAGAYILARYALNHPDTVEGLVLINIDPNAKRWMDWAAHKLTGLTSSIPEMILGHLFSQEELSGNSELIQKYRNIITHAPNLDNIELYWNSYNNRRDLNFERGGDITLKCPVMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTASLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGHTMEVSC