Protein
Nuclear distribution protein nudE homolog 1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Function
Required for nuclear migration to the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
Similarity
Belongs to the nudE family.
Sequence
MVPNLDLETAIQIISSLETQLSELEGATKEYENDLEQVISKLKSDLLESQQQNKCNKKQITDLEIQVDELENENIQLRNKIETLQLESDRRLERNVLLEHELLDTKEALQKLRVSKEEATSGETRRNTRSLPSQNKKMKLFKDTIKVSTTSSTLYLQNMAKTNNAARSHCNIPNTQITQSTVIATTSSV