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NDL1

Gene
NDL1
Protein
Protein NDL1
Organism
Arabidopsis thaliana
Length
346 amino acids
Function
Interacts with the heterotrimeric G protein beta subunit GB1 and plays an significant role in GB1-dependent regulation of lateral root formation. Involved in a signaling pathway that modulates root auxin transport and auxin gradients. Acts partially by positively regulating the auxin carrier PIN2 and AUX1 (PubMed:19948787). Acts, together with GB1 as positive regulator of meristem initiation and branching. GB1 and NDL1 positively regulate basipetal inflorescence auxin transport and modulate MAX2 expression in shoots, which regulates organ and lateral meristem formation by the establishment and maintenance of auxin gradients (PubMed:24223735).
Similarity
Belongs to the NDRG family.
Mass
38.299 kDa
Sequence
MTDSYGAVSVDVGTIYLGGKEHRVKTASGVVSVIVYGDREKPALITYPDLALNHMSCFQGLFFCPEAASLLLHNFCIYHISPPGHELGAAPICPNDSVPSAENLADQILEVLNFFGLGVVMCMGVTAGAYILTLFAMKHRERVLGLILVSPLCKAPSWSEWFYNKVITNLLYYYGMCGVVKEFLLQRYFSKEVRGNVEIPESDIAQACRRLLDERQGINVLRFLDAIDRRPDISSGLKKLKCRTLIFIGDQSPFYSEAVHMAATLDRGYCALVEVQACGSMVTEEQPHAMLIPMEYFLMGYGLYRPSLFSESPRSPLSPSCISPELLSPESMGLKLKPIKTRISAA

Gene
NDL1
Protein
Nuclear distribution protein nudE homolog 1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
189 amino acids
Function
Required for nuclear migration to the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck.
Similarity
Belongs to the nudE family.
Mass
21.53 kDa
Sequence
MVPNLDLETAIQIISSLETQLSELEGATKEYENDLEQVISKLKSDLLESQQQNKCNKKQITDLEIQVDELENENIQLRNKIETLQLESDRRLERNVLLEHELLDTKEALQKLRVSKEEATSGETRRNTRSLPSQNKKMKLFKDTIKVSTTSSTLYLQNMAKTNNAARSHCNIPNTQITQSTVIATTSSV