Protein
Cellobionic acid phosphorylase
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Function
Catalyzes the reversible phosphorolysis of cellobionic acid (4-O-beta-D-glucopyranosyl-D-gluconate), a probable step in cellulose degradation. May be part of a metabolic pathway where cellobionic acid is converted into alpha-D-glucose 1-phosphate and D-gluconic acid to enter glycolysis and the pentose phosphate pathway, respectively. Produces 4-O-beta-D-glucopyranosyl-D-glucuronate from alpha-D-glucose 1-phosphate and D-glucuronate with low activity in the synthetic direction.
Similarity
Belongs to the glycosyl hydrolase 94 family. Cellobionic acid phosphorylase subfamily.
Sequence
MTRKMPTLVRPTHNGERYEITNPTAMPKAAGFLWNQKMMIQITCRGFATAQFMQPEPAKYAYAPNIEAKTFMQPEPNYYAHHPGRFVYIKDEETGRLFSAPYEPVRAPHDRFVFSAGKTDVFWVIESMGIRVEMTMGLPTHHVAELWTIKVKNLSSRPRKLSVTPYFPIGYMSWMNQSAEWNHNLNGIVASCVTPYQKAADYFKNKYLKDKTYFLCDVPPDSWEASQQAFEGEGGLHNPSALQERNLSGSDARYETPTAAVQYKIALGTGEQQEYRFLFGPAHDEAEIGAMRSKYLSKEGFEQTAADYAAYMARGRGCLHVETPDKDLDNFINNWLPRQVYYHGDVNRLTTDPQTRNYLQDNMGMNYIKPEVSRRAFLTAIAQQEATGAMPDGILLVEGAELKYINQVPHTDHCVWLPVTLEAYLNETGDYSLLKEKVPSANGDKLTVFERFCRAMDWLLKSRDHRGLSYIAQGDWCDPMNMVGYKGKGVSGWLTLATAFSLNIWAKVCDHEGETDLAKRFREGADACNAAANEHLWDGEWFARGITDDNVVFGIKEDKEGRIWLNPQSWSILSGAASPEQIDKMLPQIDSHLNTPYGIQMFGPPYTKMREDVGRVTQKAIGSAENAAVYNHAGIFFIHSLYELGAQQDRAFTLLRQMLPGPTDTDYIQRGQLPIYIPNYYRGAWKECPRTAGRSSQLFNTGTVSWVYRCIIEGLCGLRGDGEGLLIRPQLPSSWNSMKVTREFRGATFNVDIRRGNVKEVTVRNGDKVLPAPHVKDIEPGQTYNLTVTIP