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NCU00565

Gene
NCU00565
Protein
Lipoyl synthase, mitochondrial
Organism
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Length
430 amino acids
Function
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
Similarity
Belongs to the radical SAM superfamily. Lipoyl synthase family.
Mass
46.902 kDa
Sequence
MASPVPIQRLQAPLRRSLARAAALSTRSYATIPSGPSSQPTSQESSSAASASAPATKPRPTYFKDTTLASLDDFIANQSSAAPLAPSEAYTLRTAEVGPAGKKRTITRLPEWLKTPIPSAGANPEFAKIKADLRGLNLHTVCEEARCPNIGECWGGSNKAAATATIMLMGDTCTRGCRFCSVKTSRKPPPLDPHEPENTAEALARWGLGYVVLTSVDRDDLADGGARHFAETIRRIKQKKPTLLVEALTGDFAGDLDMVKIVAESGLDVYAHNVETVENLTPYVRDRRATFRQSLKVLEHVKKVRGKEGIITKTSIMLGLGETEEELWEALRELRKVDVDVVTFGQYMRPTKRHLAVEKYITPDEFELWRQRALDMGFLYCASGPLVRSSYKAGEAFIENVLRKRSGEKVVSEALGQAVAAEEATSVQSS