Organism
African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983)
Function
May play an immunosuppressive role by inhibiting lymphocyte proliferation and subsequently facilitating viral replication and generalization of infection (PubMed:9525608). Responsible for viral hemadsorption, which may help viral spread. Increases virus replication in the tick vector at the step of virus uptake or replication in the tick gut. May play a role in the host Golgi reorganization to yield viral factories (By similarity).
Similarity
Belongs to the asfivirus CD2 homolog protein family.
Sequence
MIIILIFLIIPNIVLSIDYWVSFNKTIILDSNITNDNNDINGVSWNFLNNSLNTLATCGKAGNFCECSNYSTSLYNIAHNCSLTIFPHNDVFGTPYQVVWNQIINYTIKLLTPVTPPNITYNCTNFLITCKKNNGTNTIIYFNINDTNVKYTNESILEYNWNNSNFNNFTATCIINNTINSSNDTQTIDCINTLLSSYLDFFQVASYMFYMIIFIATGIIASIFISIITFLSLRKRKKHVEEIESPSPSESNEEEQCQHDDTTSIHEPSPREPLLPKPYSRYQYNTPIYYMRPLTQPLNPSPLPKLCPPPKPCPPPKPCPPPKPCPPPKPCPSSESCSPPESYSLPKPLPNIPLLPNIPPLSTQNISLIHVDRII