MUTYH

Adenine DNA glycosylase

546 amino acids

Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.

Belongs to the Nth/MutY family.

60.069 kDa

MTPLVSRLSRLWAIMRKPRAAVGSGHRKQAASQEGRQKHAKNNSQAKPSACDGMIAECPGAPAGLARQPEEVVLQASVSSYHLFRDVAEVTAFRGSLLSWYDQEKRDLPWRRRAEDEMDLDRRAYAVWVSEVMLQQTQVATVINYYTGWMQKWPTLQDLASASLEEVNQLWAGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLCRARQRVEQEQLLASGSLSGSPDVEECAPNTGQCHLCLPPSEPWDQTLGVVNFPRKASRKPPREESSATCVLEQPGALGAQILLVQRPNSGLLAGLWEFPSVTWEPSEQLQRKALLQELQRWAGPLPATHLRHLGEVVHTFSHIKLTYQVYGLALEGQTPVTTVPPGARWLTQEEFHTAAVSTAMKKVFRVYQGQQPGTCMGSKRSQVSSPCSRKKPRMGQQVLDNFFRSHISTDAHSLNSAAQ

Mutyh

Adenine DNA glycosylase

516 amino acids

Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.

Belongs to the Nth/MutY family.

57.919 kDa

MKKLRASVRSHKKQPANHKRRGKCALSSSQAKPSGLDGLAKQKREELLKTPVSPYHLFSDIADVTAFRRNLLSWYDQEKRDLPWRKRVKEETNLDRRAYAVWVSEVMLQQTQVATVIDYYTRWMQKWPTLQDLASASLEEVNQLWSGLGYYSRGRRLQEGARKVVEELGGHVPRTAETLQQLLPGVGRYTAGAIASIAFDQVTGVVDGNVIRVLCRVRAIGADPTSSFVSHHLWDLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCNHCPVQSLCRAHQRVGQGRLSALPGSPDIEECALNTRQCQLCLPSTNPWDPNMGVVNFPRKASRRPPREEYSATCVVEQPGATGGPLILLVQRPNSGLLAGLWEFPSVTLEPSGQHQHKALLQELQHWSAPLPTTPLQHLGEVIHVFSHIKLTYQVYSLALEGQTPASTTLPGARWLTWEEFRNAAVSTAMKKVFRVYEEHRRGTCKGSKRPQVCTPSSRKKPSRGQQVLDRFFQRHIPTHKPNSTTQ

Mutyh

Adenine DNA glycosylase

515 amino acids

Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.

Belongs to the Nth/MutY family.

57.723 kDa

MKKLQASVRSHKKQPANHKRRRTRALSSSQAKPSSLDGLAKQKREELLQASVSPYHLFSDVADVTAFRSNLLSWYDQEKRDLPWRNLAKEEANSDRRAYAVWVSEVMLQQTQVATVIDYYTRWMQKWPKLQDLASASLEEVNQLWSGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFDQVTGVVDGNVLRVLCRVRAIGADPTSTLVSHHLWNLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCSHCPVQSLCRAYQRVQRGQLSALPGRPDIEECALNTRQCQLCLTSSSPWDPSMGVANFPRKASRRPPREEYSATCVVEQPGAIGGPLVLLVQRPDSGLLAGLWEFPSVTLEPSEQHQHKALLQELQRWCGPLPAIRLQHLGEVIHIFSHIKLTYQVYSLALDQAPASTAPPGARWLTWEEFCNAAVSTAMKKVFRMYEDHRQGTRKGSKRSQVCPPSSRKKPSLGQQVLDTFFQRHIPTDKPNSTTQ