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MTPN

Gene
mtpn
Protein
Myotrophin homolog
Organism
Dictyostelium discoideum
Length
120 amino acids
Function
May regulate NF-kappa-B transcription factor activity. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex (By similarity).
Similarity
Belongs to the myotrophin family.
Mass
12.998 kDa
Sequence
MEEQNDFTWAVKNGDIANVKKSVEAKKDLISITDGNKRGPCHWAADFNQVEVLEYLISKGAKFDNTDDYGITPLLAAVYEGHTGAVELLVKKGANKSVVGPDGQTAYDAAEKADIKALLK

Gene
MTPN
Protein
Myotrophin
Organism
Bos taurus
Length
118 amino acids
Function
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity).
Similarity
Belongs to the myotrophin family.
Mass
12.895 kDa
Sequence
MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKALLQ

Gene
MTPN
Protein
Myotrophin
Organism
Canis lupus familiaris
Length
118 amino acids
Function
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity).
Similarity
Belongs to the myotrophin family.
Mass
12.895 kDa
Sequence
MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKALLQ

Gene
MTPN
Protein
Myotrophin
Organism
Gallus gallus
Length
118 amino acids
Function
Regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex (By similarity).
Similarity
Belongs to the myotrophin family.
Mass
12.886 kDa
Sequence
MSDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHNITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKTLLQ

Gene
mtpn
Protein
Myotrophin
Organism
Danio rerio
Length
118 amino acids
Function
Regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex (By similarity).
Similarity
Belongs to the myotrophin family.
Mass
12.749 kDa
Sequence
MGDKELMWALKNGDLDEVKNILVKAEDVNRTLEGGRKPLHYAADCGQAEMLEFLLSKGADVNAPDKHGITPLLSATYEGHVTCVKILLEKGADKNRKGPDGLSAFEAAESEAIKALLE

Gene
MTPN
Protein
Myotrophin
Organism
Homo sapiens
Length
118 amino acids
Function
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy.
Similarity
Belongs to the myotrophin family.
Mass
12.895 kDa
Sequence
MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTAFEATDNQAIKALLQ

Gene
Mtpn
Protein
Myotrophin
Organism
Mus musculus
Length
118 amino acids
Function
Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer.
Similarity
Belongs to the myotrophin family.
Mass
12.861 kDa
Sequence
MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEATDNQAIKALLQ

Gene
Mtpn
Protein
Myotrophin
Organism
Rattus norvegicus
Length
118 amino acids
Function
Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer (By similarity). Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy.
Similarity
Belongs to the myotrophin family.
Mass
12.861 kDa
Sequence
MCDKEFMWALKNGDLDEVKDYVAKGEDVNRTLEGGRKPLHYAADCGQLEILEFLLLKGADINAPDKHHITPLLSAVYEGHVSCVKLLLSKGADKTVKGPDGLTALEATDNQAIKALLQ

Gene
mtpn
Protein
Myotrophin
Organism
Xenopus laevis
Length
118 amino acids
Function
Regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex (By similarity).
Similarity
Belongs to the myotrophin family.
Mass
12.744 kDa
Sequence
MGDKEFMWALKNGDLDAVKEFVAGGVDVNRTLEGGRKPLHYAADCGQDEIVEFLLAKGANINAADKHGITPLLSACYEGHRKCVELFVSKGADKNVKGPDGLNAFESTDNQAIKDLLH

Gene
mtpn
Protein
Myotrophin
Organism
Xenopus tropicalis
Length
118 amino acids
Function
Regulates NF-kappa-B transcription factor activity. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex (By similarity).
Similarity
Belongs to the myotrophin family.
Mass
12.737 kDa
Sequence
MGDKEFVWAIKNGDLDAVKEFVLGGEDVNRTLDGGRKPMHYAADCGQDEVLEFLLSKGANINAADKHGITPLLSACYEGHRKCVELLLSKGADKTVKGPDGLNALESTDNQAIKDLLH