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MTN2

Gene
MTN2
Protein
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 2
Organism
Arabidopsis thaliana
Length
254 amino acids
Function
Enzyme of the methionine cycle that catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Contributes to the maintenance of AdoMet homeostasis and is required to sustain high rates of ethylene synthesis.
Similarity
Belongs to the PNP/UDP phosphorylase family. MtnN subfamily.
Mass
27.462 kDa
Sequence
MEGVMGQVEKRPISTIVFIVAMQKEAQPLINRLRLVEEVNTPFPKEVTWIMFKGMYKDLNINIVCPGKDSTLGVESVGTVPASLVTYASILAIQPDLIINAGTAGGFKAKGACISDVYVVSTVAFHDRRIPVPVLDIYGVGMRNTFPTPNLIKELNLKVGRLSTGDSMDMSPHDEESITANDATVKDMEGAAVAYVADIFKVPTILIKGVTDIVDGNRPTSEEFLENLAAVTAKLDESLTKVIDFISGKCLSDL