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MTERF3

Gene
MTERF3
Protein
Transcription termination factor 3, mitochondrial
Organism
Homo sapiens
Length
417 amino acids
Function
Binds promoter DNA and regulates initiation of transcription (PubMed:17662942). Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity). Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (By similarity).
Similarity
Belongs to the mTERF family.
Mass
47.971 kDa
Sequence
MALSAQQIPRWFNSVKLRSLINAAQLTKRFTRPARTLLHGFSAQPQISSDNCFLQWGFKTYRTSSLWNSSQSTSSSSQENNSAQSSLLPSMNEQSQKTQNISSFDSELFLEELDELPPLSPMQPISEEEAIQIIADPPLPPASFTLRDYVDHSETLQKLVLLGVDLSKIEKHPEAANLLLRLDFEKDIKQMLLFLKDVGIEDNQLGAFLTKNHAIFSEDLENLKTRVAYLHSKNFSKADVAQMVRKAPFLLNFSVERLDNRLGFFQKELELSVKKTRDLVVRLPRLLTGSLEPVKENMKVYRLELGFKHNEIQHMITRIPKMLTANKMKLTETFDFVHNVMSIPHHIIVKFPQVFNTRLFKVKERHLFLTYLGRAQYDPAKPNYISLDKLVSIPDEIFCEEIAKASVQDFEKFLKTL

Gene
Mterf3
Protein
Transcription termination factor 3, mitochondrial
Organism
Mus musculus
Length
412 amino acids
Function
Binds promoter DNA and regulates initiation of transcription (By similarity). Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes (PubMed:17662942, PubMed:23300484). Required for normal mitochondrial function (PubMed:17662942, PubMed:23300484). Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (PubMed:17662942, PubMed:23300484).
Similarity
Belongs to the mTERF family.
Mass
47.357 kDa
Sequence
MALLAQQLPRRFNSVKLTSFIKAKQVTKRSARAGKAVLPGFSAQPLLSSDTSFLRRGIKTYRTLFWNRFHSASTNRTKSSAESTLLPSVAEQQERILSLESELPLEEVDDLPPLSPLQSVSEEEAIQIAAYSPLPISSFTLADYVDHSKTLQKLVQLGVDLSKIEKHPDAANLLLRLDFEKHIKQILLFLKDLGLEDNQLGPFLTKNYAIFSEDLENLKTRVAYLQSKNFSKTDIARMVKNAPFLLSFSVERLDNRLGFFQKELELNVKKTRDLVVRLPRLLTGSLEPVKENMKVYHLELGFKHNEIQHMVIKIPKMLTANKRKLTEIFDYVHNVMNIPHHIIVKFPQLFNTRVFKIKERHLFLAYLGRAQYDPAKPNYVSLDKFVSFPDKIFCKEIAKASLNDFEKFLKTL

Gene
Mterf3
Protein
Transcription termination factor 3, mitochondrial
Organism
Rattus norvegicus
Length
409 amino acids
Function
Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function. Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (By similarity).
Similarity
Belongs to the mTERF family.
Mass
46.666 kDa
Sequence
MALLAQQLSRWFNSVKLSSFIKATQVTKHSAGLGKNASAQALLSSDTCFLQWGIKTDRALFSWSSFQSANTTRRKSSTNSTLLPSVSEQPEKIPRLESELPLEELDDLPPLSPLQPVSEEEAIQIAAYSPLPLSSSTLADYVDHSETLQKLVQLGVDLSKIEKHPDVANLLLRLNFEKDIKQILLFLKDLGLEDNQLGPFLTKNYAIFSEDLENLKTRVAYLQSKNFSKTDIACMVKNAPFLLSFSVERLDNRLGFFQKELELSVKKTRDLVVRLPRLLTGSLEPVKENMKVYRLELGFKHNEIQHMVTKIPKMLTANKRKLTETFDYVHNVMNIPHHIIVKFPQVFNTRVFKIKERHLFLAYLGKAQYDPAKPNYVSLDKFVSFPDEVFCKEIAKASVNDFEKFLKTL

Gene
MTERF3
Protein
Transcription termination factor 3, mitochondrial
Organism
Gallus gallus
Length
405 amino acids
Function
Binds promoter DNA and regulates initiation of transcription. Required for normal mitochondrial transcription, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function (By similarity).
Similarity
Belongs to the mTERF family.
Mass
45.633 kDa
Sequence
MAVWARQVARCGWLRAAGLLGLRSRSGAARACCGAAPLPALLSGHRLPPWRLRVSVDYAQPSRAKGEACAPRSSLPVAVKQEQAAPETVSDLSAAKLCEDWDDVPPSSALEEISEEEAVKIIADPLLPPQSSTLRDYVDHSETLTKLVHLGVDLSQVEKRQKAGQLLLTLDFEKDITKILLFLKDVGIEDNQLGPFLTKNPYILGEELEALETRVAYLKSKKFGNAEITQMVSRAPYLLLFSVERLDNRLGFFKNELGLSVKKTKDLVIRFPRLLTGKLEPVKENLQVCQVEFGFERNEVQQIAFKTPKILTASKKRLRQTFDYLHNIMGIPHNMLTRFPQVFNSKLLRIKERHMFLIFLGRAQYDPTKPSYISLDQLVSLPDEVFCTEIAKASMQDFEKFLKTI

Gene
mTerf3
Protein
Transcription termination factor 3, mitochondrial
Organism
Drosophila melanogaster
Length
354 amino acids
Function
Binds promoter DNA and regulates initiation of transcription (By similarity). Regulator of mitochondrial ribosome biogenesis and translation that is essential for development (PubMed:16787637, PubMed:23300484). Required for normal mitochondrial transcription and translation (PubMed:16787637, PubMed:23300484). Required for assembly of mitochondrial respiratory complexes and normal mitochondrial function (PubMed:23300484). Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit (PubMed:23300484).
Similarity
Belongs to the mTERF family.
Mass
41.267 kDa
Sequence
MFCSALRNILRNSQNAAKNATITSQIRNLRGQQSVHHEVEVLTSPGITTKQNDKKTEPAECEGSKEVALDFRNREAHVPSFNLAAYVNNSSTLQQFLSLGVDLHSIERRKGLGDFVLKLDFEKNVKPYITFLVDQGVSPDDFGRMFTKNPLLFKEDLDDLQTRVNYLKSKRFSDEARQRILTQNPYWLMFSTRRVDRRLGYFQKEFKLSGHDLRLLATREPNAITYNMEHLRKSVFTLKEEMGFNAKELSDLVVRKPRLLMIPPDDLVERFSYIHQDMGLPHAQIVQCPELLASREFRLRERHEFLKLLGRAQYDPQKDLYISPKTIVEGNNFYFVRNVAKSDLETFDLFLKTR