Protein
HTH-type transcriptional repressor MT1396
Organism
Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
Function
Negatively regulates the expression of the efflux pump MT0201 upon chloramphenicol exposure. Acts by binding to the MT0201 promoter region.
Sequence
MQTTPGKRQRRQRGSINPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLNAMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIRAALSPKTARLGAQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVVLDRLSRKSQSAGSGPSAIEHPVAIDPATTPLLAHATGRGHRIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPGARAKAVAR