Mss51

Putative protein MSS51 homolog, mitochondrial

467 amino acids

52.283 kDa

MAPRSRRRKHKKPPPVTPMPDIPPTDVSAVRPALPEPGPSIDALGFIALDSDVPGLPQRILQRLNMKSYEEYKLVIDGGTPVPSFGFRCQQEMFQRMEDTFRFCAYCKALPHGLSSCKVLRHCKRCRNVYYCDAECQRSDWPAHRKVCGELRLVAVDRVMEWLLVTGDFVLPSGPWPWLPEEIQNWDTWFSMRGLQLESTLNALLGSHAMTMLWASLGRPRPDPDVLHGSLKRLMTDVLSRPLTLGLGIRTLAIDVGKTGGSTLHVVGASHVETFLIRSGDYDELGYMFPENLGFRVIMVGVDVSADLLQSSSSLPLEPGTVQLSGHRALYHDFWEEQIETGNLAHPDLVAAFHPGFHASPGLMEAWLPTLLLLRDYEIPTLITVYSQQELEASLQVLVNLDTHIIACGANPFASLKPEQVYSKPNKQPVYSSAYYIVFRGCSSCQLDKQQVEEEPDEFSVVESNPN

MSS51

Putative protein MSS51 homolog, mitochondrial

460 amino acids

51.289 kDa

MAPRSRRRRHKKPPSSVAPIIMAPTTIVTPVPLTPSKPGPSIDTLGFFSLDDNVPGLSQLILQKLNMKSYEEYKLVVDGGTPVSGFGFRCPQEMFQRMEDTFRFCAHCRALPSGLSDSKVLRHCKRCRNVYYCGPECQKSDWPAHRRVCQELRLVAVDRLMEWLLVTGDFVLPSGPWPWPPEAVQDWDSWFSMKGLHLDATLDAVLVSHAVTTLWASVGRPRPDPDVLQGSLKRLLTDVLSRPLTLGLGLRALGIDVRRTGGSTVHVVGASHVETFLTRPGDYDELGYMFPGHLGLRVVMVGVDVATGFSQSTSTSPLEPGTIQLSAHRGLYHDFWEEQVETGQTHHPDLVAAFHPGFHSSPDLMEAWLPTLLLLRDYKIPTLITVYSHQELVSSLQILVELDTHITAFGSNPFMSLKPEQVYSSPNKQPVYCSAYYIMFLGSSCQLDNRQLEEKVDGGI

Mss51

Putative protein MSS51 homolog, mitochondrial

446 amino acids

49.95 kDa

MAPRSRRRKHKKPPPVIPMIEIPPTEVSPVSPALSKPGPSIDALGFISLDNNVPGLSQLILQKLNMKNYEEYKLVINGGTPVSSFGFRCQQEMFQKMEDTFRFCAYCKVLPHGLSNCKVLRHCKRCRNVYYCDTECQRSDWPAHRKVCRELRLVAVDRVMEWLLVTGDFVLPSGPWPWLPEDIQNWDTWFSMRGLQLESTLNALLGSHSMTMLWASLGRPRPDPDVLHGSLKRLMTDVLSRPLTLGLGLRTVAIDVGKTGGSTLHVVGASHVETFLIRSGDYDELGYMFPEHLGFHVIMVGVDVATDLLQSSSSLSLEPGTIQLSGHRALYHDFWEEQIETGILAHPDLVAAFHPGFHASPGLMEAWLPTLLLLRDYEIPTLITVYSQQELEASLQILVNLDTHIIACGANPFASLKPEQVYSNPNKQPVYSSAYYIMFLGSSPAN

MSS51

Protein MSS51, mitochondrial

436 amino acids

Has a dual role in the assembly of cytochrome oxidase subunit 1 (COX1). It has a regulative function on COX1 synthesis, acting as a translational activator specific for the COX1 mRNA, and it also binds to newly synthesized COX1 protein. Together with COX14, may act as a chaperone that binds efficiently unassembled COX1 and prevents it from unproductive aggregation. When bound to COX1, MSS51 is unable to interact with the COX1 mRNA and translation is halted. This may be a feedback control that ensures that COX1 is only produced as long as potentially harmful assembly intermediates are not accumulating.

Belongs to the MSS51 family.

50.88 kDa

MTVLYAPSGATQLYFHLLRKSPHNRLVVSHQTRRHLMGFVRNALGLDPPPSPEDPTPENRFHPWDQSPSVDLRERAAKIRTLAHCPVTGKDINYTCPLSGIPTHHSREAWEMDKAYHDSKKYEILKKVNIYEHDLRSGRPFPEFDFPQQQGYDKAVNLTNWDLFFYTRSFYSMDTEFQLAAVTKMLSYPITIGSLLHKFSPYSLNPKGPITLEGLKSLAALRYTLYPLENRSLPTTTKNRAMRIFILGARAEAQLPGHVWKQLQFLFPEQSFEIHFIGPECLYKRDKQEYVKSTTPVVQRVDETLKFIYRTNFFEVFHEAQDFFPYDPYMDVFFTFHPGYASPESHGSWMGETMKALLETKCAIFTTGFNKKDLTDDINLVKSKYGKEMDVLMEPVRNVFGSTKWELNDMNPQEVYQFNMYIAGFRGKRYHTIKRQ

mss51

Protein mss51

378 amino acids

Has a dual role in the assembly of cytochrome oxidase subunit 1 (cox1). It has a regulative function on cox1 synthesis, acting as a translational activator specific for the cox1 mRNA, and it also binds to newly synthesized cox1 protein (By similarity).

Belongs to the MSS51 family.

43.6 kDa

MSFLKNLFKKKSPTHELFHPLSRSPLTALRRRSEHIKQVYRCPISGKSVEYECPESGFPTHCNRTHWEQDKIHQSLIPKLRQINEDYHDLARPNPLPELLKLPGPMEEDEVVSLLSWDSFFYTRDFPKFQSSRTARHITSLLTYPMSIGAILHKNSPYNLKNGLTPQGLQSLTALRYMLHRPLSAQSTDPRPTRIFVLGATKECSLPPSIWLQGLNFLFPGRLFQLHFIGPEVVVPSKQPNLPSPLSLHFHQDYYHNLHRVGAFEPFDPYYDTFFLPMPLISHPLYSSSWIPTLHDLVSTRCSVWLTSPSSQRTTKDLEVLNNVLKDSIEPLLLPTVNKFASLGWSVDDSNLHEVYHANQEVFGFRALYYNVQNVSKE