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ML0131

Gene
ML0131
Protein
Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase
Organism
Mycobacterium leprae (strain TN)
Length
382 amino acids
Function
Catalyzes the reduction of the keto moiety of phthiodiolone dimycocerosates (DIM B) and glycosylated phenolphthiodiolone dimycocerosates to form the intermediate compounds phthiotriol and glycosylated phenolphthiotriol dimycocerosates during phthiocerol dimycocerosates (DIM A) and glycosylated phenolphthiocerol dimycocerosates (PGL) biosynthesis.
Similarity
Belongs to the mer family. Phthiodiolone/phenolphthiodiolone dimycocerosates ketoreductase subfamily.
Mass
41.258 kDa
Sequence
MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALVPRSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVTDAGRRNPAVTAQAAATLHLLTRGKAMLGIGVGEREGNEPYGVEWTKPVARFQEALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPEIWVAAHGPRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSITPAAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGADFAGVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHGLKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL