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MK1503

Gene
MK1503
Protein
Probable inosine/xanthosine triphosphatase
Organism
Methanopyrus kandleri (strain AV19 / DSM 6324 / JCM 9639 / NBRC 100938)
Length
170 amino acids
Function
Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.
Similarity
Belongs to the YjjX NTPase family.
Mass
18.316 kDa
Sequence
MKVRVGTTNPVKVRATERAFLRTFPDREITVEAVSVDPGVPPQPVGMEEVHQGAKNRAREAWNRGSYSVGLEAGLIRVGDVYVDLHVAVVRDPKGRETVGTSPGFQLPPDVTEEALSGEEVGEVFSELVGVREIGKRSGAIGVLSNGKVLREDLCELAILMALIGLETSR