Protein
MICOS complex subunit MIC60
Organism
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / CBS 544.65 / FGSC A1164 / JCM 1740 / NRRL 181 / WB 181)
Function
Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a role in keeping cristae membranes connected to the inner boundary membrane. Also promotes protein import via the mitochondrial intermembrane space assembly (MIA) pathway (By similarity).
Similarity
Belongs to the MICOS complex subunit Mic60 family.
Sequence
MLRSSFTQSRQLLLSPARSRTAAQWLPKAGASNRLAGQRFFADAKPPVTGAPTPASPSSESPIPPESVPKPSPAAEAPPPPPPPPAPARKTGRFRKFLLYLILTSGFAYGGGIFLALKSDNFHDFFTEYVPYGEDCVLYFEERDFYRRFPNTLRNQNRAPKDEGHTVTIPSKSGLSWKVADEESGADVSQKGPHMSALDNGEKAQLKPGAAKPEEKVAAVEKAKAESAAKEQSSDDKKKVQEEPKKPAAPAVTPIEFATVSEGDEEVVQELVKTFNDIITVIGADENAHKFSGAVNKAKEELRTIGEKIIAIRNEARNAAQEEIKQAHATFDESARELIRRFEEARAHDAAQYREEFEVERERLARAYQEKVNTELQRAQEVAEQRLKNELVEQAIELNRKYLHEVKDLVEREREGRLSKLNELTANVNLLEKLTTDWKEVIDTNLKTQQLQVAVDAVRSVLERSTVPRPFVRELVAVKELAAGDPVVEAAIASINPTAYQRGIPSTSQIIERFRRVADEVRKASLLPEDAGIASHAASLVLSKVMFKKDAVAGSDDVESVLLRTEHLLEEGNLDDAAREMNTLKGWAKILSKDWLSDVRRVLEVKQALEVIETEARLQCLRVE