MGAT4D

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D

374 amino acids

May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.

Belongs to the glycosyltransferase 54 family.

43.743 kDa

MRTKQVNLLITLVAVALFSFSCFSIYRITQTNNQLINCRNHILEFKENMLHLRNKTEKNTQEMMKVLNRMKYEITKREILSGNLVAQKADILNKNETVSNTFEDLKFFFPHLRKEGRIYPDVIIGKGKTGVSFALGISTVNRGNYSYLKQTLTSVVSRMTLSQEKDSVVIVLVADSNEDYLHSVVKMITKKFKRQVRSGSLEVISIPAFLYSSMLNAKHLAEASQKLASWRIKQVLDFCILLLYAQPKAKYYLQLEDDIIAKEMYFTKITDFVGNISSNNWFFIEFSMLGFIGKLFRSEDLTHFVRFFLMFYKEKPIDWLLNDIFQVKVCDAGEDLRNCMKRKKQIRIQYKPSLFQHVGIHSSFPRKEQYEKKI

Mgat4d

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D

373 amino acids

Isoform 2: May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.

Belongs to the glycosyltransferase 54 family.

43.3 kDa

MKAKNVNLLFAFVAVLLFGFSCFCISRMNQTNNQLINCRNHVLEFKEIMLRLKNKSENHHQDLMQVLYQMKRKAAHTTRSSGNFLEKKGSILSQHETLPNQFEVLKYFLPHLRTAGKLYPAIATSKGRAGVSFALGISTINRGNHTYLKQTLTSVLSRMTPEEEEDSVVIVSVADTDESYLKSVVRMVKTKFRKQVQSGVLEVISIPTLFYPQTLLDKKTKTDSESWQIKQVLDFCILMLYAQPKATYYLQLEDDIVAKKMYFTKMKDFVNSLTSKNWFFIEFSVLGFIGKLFRSKDLTDFVHFFLMFYETKPIDILLDDIFLIRVCISGEPVRSCLQRKKGFRIQYRPSLFQHVGTQSSFPGREQHLKDNYY

Mgat4d

Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase-like protein MGAT4D

372 amino acids

May play a role in male spermatogenesis. In vitro acts as inhibitor of MGAT1 activity causing cell surface proteins to carry mainly high mannose N-glycans. The function is mediated by its lumenal domain and occurs specifically in the Golgi. A catalytic glucosyltransferase activity is not detected. May be involved in regulation of Sertoli-germ cell interactions during specific stages of spermatogenesis.

Belongs to the glycosyltransferase 54 family.

43.112 kDa

MKTKNVNLLFALVAVLLFGFSCFCISRMNQTNNQLINCRNHVLEFKETMLRLKNKSENNHQNLVKVLHQLKHKVAPAKPSGSILEKKVNMLDQDETVFNQFEVLKFFLPHLRTAGNIYPDIAIGRQRAGVSFALGITTIDRGNHTYLKQTLTSVLSRMTPEEEEDSVVIVSVADTDENYLKSVVHMVKTRFRKQVQSGALEVISIPALFYPQTLLEKKTTKNAKNWQIKQVLDFCILMLYAQPKATYYLQLEDDIVAKKMYFTKMKDFVNSVTSKDWFYIEFSVLGFIGKLFRSKDLMDFVHFFLIFYRAKPIDVLLDDIALLRMCSFGGPLRSCLQLKREVRVQYKPSLFQHVGTHSSFPGREQHLKDHYY