Protein
DNA (cytosine-5)-methyltransferase 1A
Organism
Oryza sativa subsp. japonica
Function
Probably methylates CpG residues and maintains DNA methylation (PubMed:14513380, PubMed:24535433). May be involved in methylation-dependent gene silencing (PubMed:14513380). May play a minor role in the maintenance of DNA methylation (PubMed:24535433).
Similarity
Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
Sequence
MAKSPRSVVTTGTKRRRAKVHKEDEPVENENLESEFDVSKKESNGATEPGNEPVASKRPKRAAACSNFKEKSLDLSEKDSIITIKESRVEEKEIEAVNLTRTGPEDGQPCRKIIDFILHDGDGNLQPFEMSEVDDIFITALIMPLDDDLEKDRGKGICCSGFGRIENWAISGYDEGAAVIWVSTETSDYKCVKPASSYRSYFEHFSEKARVCVEVYKKLARSVGGNPQVDLEELIAGVVRSINSNRSFNGTVTKDFVISSGEFIYKQLIGLDHTAGNDDEMLATLPVLVALKDECKSRAGFTHLPAMPSNGTLRIKDGQDKGLTEDEDAKLARLLQEEEEWKMMKQRGKRGTSQKNIYIKICETEIANDYPLPAYYKPYNQEMDEYIFDSDIGMYSDDVPVRILDNWALYNSDSRLISLELIPMKAGAENDIVVFGSGFMREDDGSCCSTAELAQLHSSSSKSGREDPGVPIYLSPIKEWVVEFGGSMICITIRTDVAWYKLRQPTKQYAPWCEPVLKTARLAVSIITLLKEQSRASKLSFAEVIKKVAEFDSRHPAFISSKAPTVERYVVVHGQIILQQFADFPDESVKRCAFITGLLAKMEESRHTKLAIKKKSQQMRGENLNPSAKMGPILRKKLMRATTTMLISKIWGEYYATYFPGDTKEEDQNEPKEIDDDQEENEDNDAEEEVNVQDEKATRTPPSTRSRKSSADTRKEIKWEGQTAGKTVSGEVLYKCVIVQDLSISVGATVTTEDDSGETIMCFVEYMYEKLDGKNMIHGIILQEGSQTVLGNAANDREVFLTNDCLEFEASDIKELVTVNIQSLPWGHKYRKENSEAKRIEKAKAEERKRKGLPVEYICKSLYWPEKGGFFSLPYDKIGNGTGICSSCERKPVGNEFKLLSESSFVFENITYNIHDFLYIRPEFFSQGEGHETYKAGRNVGLKPYAVCHLLSVHGPAGSRKANPESTKVKVRRFYRPDDISSTKAYSSDIREVYYSEDIISVPVVMIEGKCEVRLKDDLPNSDLPAVVEHVFCCEYLYDPANGALKQLPPNVRLVTLTRKVPASKKNKGKQICDIELGGSDKPKDGQSENCLATLDIFAGCGGLSEGLQRSGLSLTKWAIEYEEPAGDAFGENHPEAAVFVENCNVILKAIMDKCGDSDDCISTSEAAERAAKLSEDKIKNLPVPGEVEFINGGPPCQGFSGMNRFNQSPWSKVQCEMILAFLSFAEYFRPRFFLLENVRNFVSFNKGQTFRLTLASLLEMGYQVRFGILEAGAYGVAQSRKRAFIWAAAPGETLPEWPEPMHVFASPELKITLPDGKFYAAVKSTAAGAPFRSITVRDTIGDLPAVENGAGKPTIQYGSGPVSWFQKKIRSDMASLNDHISKEMNELNLIRCKHIPKRPGCDWHDLPDEKVKLSTGQMVDLIPWCLPNTAKRHNQWKGLYGRLDWEGNFPTSVTDPQPMGKVGMCFHPEQDRIITVRECARSQGFPDSYRFAGNIQNKHRQIGNAVPPPLAYALGRKLKQAIDAKR