Protein
Neutral protease 2 homolog MEP6
Organism
Coccidioides posadasii (strain C735)
Function
Secreted metalloproteinase that allows assimilation of proteinaceous substrates. Shows high activities on basic nuclear substrates such as histone and protamine. May be involved in virulence (By similarity).
Similarity
Belongs to the peptidase M35 family.
Sequence
MRLSSSLIALVALAGQALALPFNELAERDTGLDVKLIPIGNTRVKAIITNNADHEMSFVKYNTLFDSSPVRKVQISKDGSIIPFKGIHLYYDIDNLPKEAYKTLAPGASAEAEFDIAETSDLSAGGSFKISAEGSIPVIDGQGTKPTSSIRFKANTLTMDIDGEMASRVASAIPELNKRTRVDNQTCTGQYAQLLQGGLRTCATYAQRAAQAASGGNAQKFQEYFKTTNQQTRQNVARRFQAIAQECSSANQGRTIYFCQDVYGYCQGAIAYTVPDRSHVVNCPAYWSLPPVLNRGLGPDHGYVIVHEFTHAPSVFSPGTVDHAYGYEQCRRLNAQQSLNNADSYSLFAADVSRN