Function
Rust effector delivered into infected tissues to modulate host functions and contribute to pathogen virulence (PubMed:30283062). Binds the TGA1a-binding DNA sequence to repress the expression of genes involved in immune responses such as the defense-related transcription factors WRKY18, WRKY27, WRKY33, MYB51, the defense-related proteins NHL3, RPP8, YLS9, AZI1, CRK11 and the jasmonate pathway and regulation genes JAZ1, ASA1, ASB1. Other genes involved in diverse mechanisms also down-regulated include the chitinase CHI, the brassinosteroid-related genes BAS1, BES1 PAR1, BEE1, the salicylic acid-related gene NPR3, the ethylene-related response genes ARGOS and ARGOS-like (ARL), EBF2, ERF6, ETR2, RTE1, the carbon metabolism-related gene EXO, as well as the red/far red light signalization-related genes FAR1, GA2OX2, PAR1, PIF3, PKS4 (PubMed:30283062).