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MBOAT7

Gene
mboat7
Protein
Lysophospholipid acyltransferase 7
Organism
Xenopus laevis
Length
474 amino acids
Function
Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
Similarity
Belongs to the membrane-bound acyltransferase family.
Mass
54.624 kDa
Sequence
MSPNELTYLAILLGSAPLGFLFKNGSPQVKQRGSAAVGVALTLITCHIHSLHSAITILGTWLIIKILPRSCHFPTLGWTFTYLLFFRTITYFDIPAPTPFTNAVQLLLTLKLVSLANEVQDFYRAKKQEVTSFSKPSAISTIPSIPSLREMFYYSYCYIGLMTGPFYRYKTYYDWLHQIDPASIPSWKPLVSRLKPAPVFGVLFLIASQYFPLDYVKTDEFYEQAFLYRLFYMVPTFFIFRMRFYVAWIFAECGCISAAFGAYPVSAKSRSGGGPTVEYAPLERNAEGAKVELEYDYETIKNIDCYGADFCVKVKDGMRYWNMSVQWWLAQYIYKNSPVKSLVFGSAWTMLVSAYWHGIHPGYYMSFLTIPLCLAAEGSMEAGLRRHVSDSGKMIFDWVHWFLKMRAYDYMCMGFVLLTFTDTYRYWQSIYFSVHVLAISLFLLGRVLALKSPRRPRNTKEEKAEAKQENRLQE

Gene
Mboat7
Protein
Lysophospholipid acyltransferase 7
Organism
Mus musculus
Length
473 amino acids
Function
Acyltransferase which contributes to the regulation of free arachidonic acid (AA) in the cell through the remodeling of phospholipids. Mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor (PubMed:23097495). Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (By similarity). Required for cortical lamination during brain development (PubMed:23097495).
Similarity
Belongs to the membrane-bound acyltransferase family.
Mass
53.436 kDa
Sequence
MTPEEWTYLMVLLISIPVGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHSLHSLITILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEIASGFHKEPTLGLLPEVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPEAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPTRLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEIAASLEYDYETIRNIDCYGTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPFRSYVLRSAWTMLLSAYWHGLHPGYYLSFMTIPLCLAAEGYLESALRRHLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSMADTLRYWASIYFWVHFLALACLGLGLVLGGGSPSKRKTPSQATSSQAKEKLREE

Gene
MBOAT7
Protein
Lysophospholipid acyltransferase 7
Organism
Bos taurus
Length
472 amino acids
Function
Acyltransferase which contributes to the regulation of free arachidonic acid (AA) in the cell through the remodeling of phospholipids. Mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor (By similarity). Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle (By similarity). Required for cortical lamination during brain development (By similarity).
Similarity
Belongs to the membrane-bound acyltransferase family.
Mass
52.765 kDa
Sequence
MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHVAQRKEMASGFSKGPPLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEMAASLEYDYETIRNIDCYNTDFCVTVREGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAERQLESALRWRLGPGGQKAWDWVHWFLKMRAYDYMSMGFVLLSLRDTLRYWASVYFCVHVLALAALGLGLALGRGGPGRRKSGAPAPSPASGKLREE

Gene
MBOAT7
Protein
Lysophospholipid acyltransferase 7
Organism
Homo sapiens
Length
472 amino acids
Function
Acyltransferase which contributes to the regulation of free arachidonic acid (AA) in the cell through the remodeling of phospholipids. Mediates the conversion of lysophosphatidylinositol (1-acylglycerophosphatidylinositol or LPI) into phosphatidylinositol (1,2-diacyl-sn-glycero-3-phosphoinositol or PI) (LPIAT activity). Prefers arachidonoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle. Required for cortical lamination during brain development (By similarity).
Similarity
Belongs to the membrane-bound acyltransferase family.
Mass
52.765 kDa
Sequence
MSPEEWTYLVVLLISIPIGFLFKKAGPGLKRWGAAAVGLGLTLFTCGPHTLHSLVTILGTWALIQAQPCSCHALALAWTFSYLLFFRALSLLGLPTPTPFTNAVQLLLTLKLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE

Gene
mboat7
Protein
Lysophospholipid acyltransferase 7
Organism
Danio rerio
Length
467 amino acids
Function
Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phospholipid remodeling pathway also known as the Lands cycle.
Similarity
Belongs to the membrane-bound acyltransferase family.
Mass
53.317 kDa
Sequence
MSPDELVYLGILAATIPVGFLFRYLSPPVKQGAALLLGLIISIATCGIHTLHSLCTVLGTWIIIKINWRSAPALSLAWTFLYLLFFRLVTWFGLPQPTPFANAIQLLLTLKMVSLANEVQSYHLERKKEVSTFTKSPVVAGLSHEPSLYDIISYSYCYVGIMTGPFFRYQTYADWLQQSSPLSLPGKEPCLQRLKMVPVYGLLFIAVNSVFPLSYVRTEDFLEHNYFYRFFYMVAIFFVFRMRFYSAWCGAEAGCISAGLGCYPQGALSKPGGGPTVKYSPDPETAVEYDFKTIQNIDCYNTDFCVKVRHGMRYWNMTVQWWLHHYIYPNAPFRAYALRAGWTMLISAYWHGLHAGYYLSFLTIPLCIAAETAMEASVRARLGPAGQNIFDWIHWFLKMRAYDYMCMGFVLLKASDTISYWSSIYFVIHIIAIVCIAVGQFMKGGRKREKRERGEGEKEDAVREKAE