Protein
Methionine aminopeptidase 2-1
Organism
Leptosphaeria maculans (strain JN3 / isolate v23.1.3 / race Av1-4-5-6-7-8)
Function
Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val).
Similarity
Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.
Sequence
MGSKSPNGEDRGPNGPSAKKAVASINPPKSAAASGLLRGALEDQDEDGDDDEGKIGADMNVSEKTANGTKKRRRNNKKKKSAQAAQQTAPPRVEIATLFHNRPYPEGEIVEYGINDENLVRTTDEEFRHLAVANNMNDEFLRDYRKAAEVHRQVRQYAQTIAKPGISMTELAREIEDGVRALVGHQGIETGDSLKAGMGFPTGLCINNVAAHWTPNPGAREVVLQHDDVLSIDFGVHVNGRIVDSAFTVAFNPMYDKLLTAVKAATNTGLKESGIDARMDYISETIQEVMESYEVMINGKPLPVKALSSLSGHNILRYKIHGDKQVPFVKTRTSQRMEEGDVFAIETFGSTGIGRTRDDVGVYGYSRNENVSTAGVHLASAKSLLKAIDENFGTLPFSRNYLERIGVKNYHLGMRSLIASGVVECYAPLVDTPGSYVAQFEHTVLLRPNCKEIISRGDDY