LYS5

Saccharopine dehydrogenase [NAD(+), L-lysine-forming]

369 amino acids

Catalyzes the NAD(+)-dependent cleavage of saccharopine to L-lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis.

Belongs to the AlaDH/PNT family.

40.612 kDa

MTAPVKLHLRAETKPLEHRSALTPTTTRKLLDAGFEVFVEKSPLRIFDDQEFVDVGATLVEEGSWVSAPEDRMIIGLKELPEESFPLSHEHIQFAHCYKDQGGWKDVLSRFPAGNGTLYDLEFLEDDNGRRVAAFGFHAGFAGAAIGVETWAFQQTHPDSENLPGVSAYPNETELVDKIKKDLAAAVEKGSKLPTVLVIGALGRCGSGAIDLARKVGIPEENIIRWDMNETKKGGPFQEIADADIFINCIYLSQPIPPFINYDLLNKETRKLSVIVDVSADTTNPHNPVPVYTIATTFDHPTVPVETTAGPKLSVCSIDHLPSLLPREASEAFSEALLPSLLQLPQRDTAPVWTRAKALFDKHVLRIGE

LYS5

L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

276 amino acids

Catalyzes the transfer of a 4'-phosphopantetheine moiety from coenzyme A to a serine residue of acceptor proteins, such as alpha-aminoadipate reductase. Necessary for alpha-aminoadipate reductase activity (By similarity).

Belongs to the P-Pant transferase superfamily. AcpS family.

29.922 kDa

MAQGSPATVAACAFCGARRTRSGMVLSTSAADGYLDDEAQFETALRLLPAADQAAVRRRRAGRAVVLASRLLRTLGCAVHTGCAPALLAFDYSRAGKPYLRSRPAPAFSVSRSDCIAVIYVREGGAVGADLASVAECLSWAPDEILQLHDVFSAAELGRLRAAAPGRARAELFAYYWSLKEAYGKFRGTGLAGDLRLADMGELDPLRRGELRTLRRTLQGKHVCLSSRWHDAGHVLSLCEAREPSPTEEICLHKVPMEEVVRLCRPSLGMEKCHVR

LYS5

L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

272 amino acids

Catalyzes the transfer of a 4'-phosphopantetheine moiety from coenzyme A to a serine residue of acceptor proteins, such as alpha-aminoadipate reductase. Necessary for alpha-aminoadipate reductase activity.

Belongs to the P-Pant transferase superfamily. AcpS family.

30.683 kDa

MVKTTEVVSEVSKVAGVRPWAGIFVVEIQEDILADEFTFEALMRTLPLASQARILNKKSFHDRCSNLCSQLLQLFGCSIVTGLNFQELKFDKGSFGKPFLDNNRFLPFSMTIGEQYVAMFLVKCVSTDEYQDVGIDIASPCNYGGREELELFKEVFSEREFNGLLKASDPCTIFTYLWSLKESYTKFTGTGLNTDLSLIDFGAISFFPAEGASMCITLDEVPLIFHSQWFNNEIVTICMPKSISDKINTNRPKLYNISLSTLIDYFIENDGL

LYS5

L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase

258 amino acids

Catalyzes the transfer of a 4'-phosphopantetheine moiety from coenzyme A to a serine residue of acceptor proteins, such as alpha-aminoadipate reductase. Necessary for alpha-aminoadipate reductase activity (By similarity).

Belongs to the P-Pant transferase superfamily. AcpS family.

29.842 kDa

MSDWLSLAKSNDPHIVVLTMDVHLSYFRDEYNFEEALRLLPFEWQCRVIQKRAHKDKVTALCNRLLQLYGCRLELNTQAIDFTQGKYGKPFVKNTESFNFSMTNGENFVSIIMANLFQTEVGIDLASINDFTSEGDLKIYEDVLSTEEYEKINNQTNLLDMKRLFAFYWSVKECYTKYLGVGLNGDLKIINVSLFSAPLINEAVSTFKLKDITFHSRWVSDNEILTYCFPAQYDFLKPIHAILNVVSVIEGIKTQFLT