Protein
dTTP/UTP pyrophosphatase
Organism
Lawsonia intracellularis (strain PHE/MN1-00)
Function
Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
Similarity
Belongs to the Maf family. YhdE subfamily.
Sequence
MTQQRVSSVFIETVPIVLASASPRRRSLLEQLGLLFKIVSVDSEPLPLSSEHPLEYVIRAAKVKAFAAAALEPRSVIIAADTVVIYTKDDVFEIIGKPQSGNDSFSMLSRFQGGKHQVITGCCIVWPLEENITSVQYEIFYDTASIQFGQWDKDILSSYVSTGESNDKAGAFSIQGIGAFLIDIIEGNYTTILGLPLPQLVKRLLKRKAIKVVLNKNSEETISSDFLTYSR