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LGALS1

Gene
LGALS1
Protein
Galectin-1
Organism
Bos taurus
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates (PubMed:1900835, PubMed:8108426, PubMed:7773775). Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Mass
14.744 kDa
Sequence
MACGLVASNLNLKPGECLRVRGEVAADAKSFLLNLGKDDNNLCLHFNPRFNAHGDVNTIVCNSKDAGAWGAEQRESAFPFQPGSVVEVCISFNQTDLTIKLPDGYEFKFPNRLNLEAINYLSAGGDFKIKCVAFE

Gene
LGALS1
Protein
Galectin-1
Organism
Bubalus bubalis
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Mass
14.716 kDa
Sequence
MACGLVASNLNLKPGECLRVRGEVAPDAKSFLLNLGKDDNNLCLHFNPRFNAHGDINTIVCNSKDGGAWGAEQREVAFPFQPGSVVEVCISFNQADLTVKLPDGHEFKFPNRLNLEAINYMSAGGDFKIKCVAFD

Gene
LGALS1
Protein
Galectin-1
Organism
Capra hircus
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates (PubMed:21210196). Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis. Has hemaglutinating activity towards human erythrocytes (PubMed:21210196).
Mass
14.798 kDa
Sequence
MACGLVASNLNLKPGECLRVRGELAADAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDDGTWGAEQREVAFPFQPGSVVEVCISFNQADLTVKLPDGHEFKFPNRLNMEAINYMSADGDFKIKCVAFE

Gene
LGALS1
Protein
Galectin-1
Organism
Cricetulus griseus
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates (PubMed:7890630). Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Mass
14.803 kDa
Sequence
MACGLVASNLNLKPGECLKVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDNGAWGTEHREPAFPFQPGSTVEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE

Gene
LGALS1
Protein
Galectin-1
Organism
Homo sapiens
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Mass
14.716 kDa
Sequence
MACGLVASNLNLKPGECLRVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQANLTVKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD

Gene
Lgals1
Protein
Galectin-1
Organism
Mus musculus
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Mass
14.866 kDa
Sequence
MACGLVASNLNLKPGECLKVRGEVASDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNTKEDGTWGTEHREPAFPFQPGSITEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE

Gene
LGALS1
Protein
Galectin-1
Organism
Sus scrofa
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Mass
14.694 kDa
Sequence
MACGLVASNLNLKPGECLKVRGEVAPDAKSFVLNLGKDSNNLCLHFNPRFDMHGDINTIVCNSKDGGAWGAEQRESAFPFQPGSVVEVCISFGQTDLTIKLPDGYEFSFPNRLNLEAIEHLAADGDFKIKCVAFE

Gene
LGALS1
Protein
Galectin-1
Organism
Pongo abelii
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Mass
14.746 kDa
Sequence
MACGLVASNLNLKPGECLRVRGEVTPDAKSFVLNLGKASNNLCLHFNPRFNAHGDANTIVCNSKDGGAWGTEQREAVFPFQPGSVAEVCITFDQTNLTIKLPDGYEFKFPNRLNLEAINYMAADGDFKIKCVAFD

Gene
Lgals1
Protein
Galectin-1
Organism
Rattus norvegicus
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation. Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase. Strong inducer of T-cell apoptosis.
Mass
14.857 kDa
Sequence
MACGLVASNLNLKPGECLKVRGELAPDAKSFVLNLGKDSNNLCLHFNPRFNAHGDANTIVCNSKDDGTWGTEQRETAFPFQPGSITEVCITFDQADLTIKLPDGHEFKFPNRLNMEAINYMAADGDFKIKCVAFE

Gene
LGALS1
Protein
Galectin-1
Organism
Ovis aries
Length
135 amino acids
Function
Lectin that binds beta-galactoside and a wide array of complex carbohydrates. Plays a role in regulating apoptosis, cell proliferation and cell differentiation (PubMed:9546655). Inhibits CD45 protein phosphatase activity and therefore the dephosphorylation of Lyn kinase (By similarity). Strong inducer of T-cell apoptosis (PubMed:9546655).
Mass
14.704 kDa
Sequence
MACGLVASNLNLKPGECLRVRGEVAADAKSFSLNLGKDDNNLCLHFNPRFNAHGDINTIVCNSKDGGAWGAEQRETAFPFQPGSVAEVCISFNQTDLTIKLPDGYEFKFPNRLNLEAINYLSAGGDFKIKCVAFE