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KXD1

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Vanderwaltozyma polyspora (strain ATCC 22028 / DSM 70294)
Length
265 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
29.006 kDa
Sequence
MSSDGEEGSFEGSQLVSQSPSINSQTYAIPIPEGMLDQLDISSSSSSAGGRDDEDEEDDDADVDVGVGSECLVGVTGQDRLIIGSGDDSDNGDGDEVHDNAHATSDVSSTAELNHVCSEETEDMDNVDEGLLDDIMNNTGGGGFVNGFEFHESEPMFDVSKYVFETLIQAINSADFSESLAFQTKTSAVINAKSLELKQLINMSKDRLVDLQDKFEKGVQTSNRIKRNLKMSREKIQFLNDEFRTNYPIEFNQARDKIIERTIDS

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain RM11-1a)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain AWRI1631)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain YJM789)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain Lalvin EC1118 / Prise de mousse)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain AWRI796)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain FostersB)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSBVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain Lalvin QA23)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain FostersO)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Saccharomyces cerevisiae (strain VIN 13)
Length
218 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
24.442 kDa
Sequence
MVTGISEENDDEETFSAVHSSTPSINSQSYAIPITEEMSSSFHDSISTTSNSSGSFDSDGSNVSDVVEQNEMDNESNVDEDLFLDNDIPQSSNLLPTDAQDPGPIFDVSRYIFDSLKQSIDSADFSEALSLQTKTSAVINSKSLELKQYIDEMKSRLTQLQEKFENGEATSKKIKRDLETSRKNIDYLNAALRVDFPIEFNQAREKILERRLNEDHDC

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)
Length
203 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
22.824 kDa
Sequence
MSDEIEDRPRTRSRTPSVDTQSYTINEEAHHIITDSDSSSSENEDGEGNETNSSDDSSESGSVERFLDEIVPTTSTSFIPNDTPDPATLFDITEYIFDSIVQSTNACDFSEAFALQAKTSAVINSKSMELKNLIEQTKVRLPELQAKFKNGTQTLRTIRKNLDNAKSRIQVMNDVLQTDYPIEFNQARDKILERTLDSDEEVI

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Zygosaccharomyces rouxii (strain ATCC 2623 / CBS 732 / NBRC 1130 / NCYC 568 / NRRL Y-229)
Length
195 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
22.018 kDa
Sequence
MDDSSSEARAGIENDTTVRSRSPSVDSQSYAIPMPEEIEEQLSEESSSFDDSNSVESNEDQILGRALPESGQHAFSQDSQEFEPMLDVSKHIFDSLMQAIDSADFSEAISLQTKTSAVINSKSTELKQLIDETKVRFSQFKERFEKGSLTAKNIRGNLRYSKDKIEKINALVRTSYPIEFNEAREKILERPLDDH

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
Length
190 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
21.013 kDa
Sequence
MSDDVDSETRSRTPSISSRQFIIPEDELATLDSENSSLDSGGEEASSGGSDAYSAAGGSTPVFSRLGQHPSTFFTGSQVAPIFDTSLYLFESLTQSLDSVDFSEALSLQTKTSATINSKSRELQLLVGEVQTHLRRLQTAFEQGQHTAQRVRHNLRDITRGVESLKQTFARSYPIEYHQALERAYERRAE

Gene
kxd1
Protein
KxDL motif-containing protein 1
Organism
Danio rerio
Length
182 amino acids
Function
As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. May also be involved in the biogenesis of lysosome-related organelles such as melanosomes.
Similarity
Belongs to the KXD1 family.
Mass
20.374 kDa
Sequence
MEPTASGIFCNRMLSMVNSEDVNAIIQAQRHMLDRFEKTNEMLINFNGLSNVRLQQMNEHFLMHTRTLIEMKKDLDSIFRRIRALKGKVAKQYPEAFSNVSESSNLEDDDDEFDPIPASVATITTTATSEQSTESCDTSPDVISPTISCCSEDPSQEHTDTPTSDSHEQPVLRDEGPDSADI

Gene
kxd1
Protein
KxDL motif-containing protein 1
Organism
Xenopus laevis
Length
180 amino acids
Function
As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. May also be involved in the biogenesis of lysosome-related organelles such as melanosomes.
Similarity
Belongs to the KXD1 family.
Mass
20.208 kDa
Sequence
MAEQVTEATASGVFCSRILNMVNTGDVNAIILAQRHMLDRFEKTNEMLLNFNGLSNVRLQQMSDRFAHHTRTLVEMKKDLDIIFRRIRMLKGKLAKQYPESFNNVHESPILEDDDDFDPTLKSAATTIATSEQSTESCDTSPSIISPAMSQDFEDLSQAPSDTPSVNGQILTDEELVHED

Gene
kxd1
Protein
KxDL motif-containing protein 1
Organism
Xenopus tropicalis
Length
180 amino acids
Function
As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor. May also be involved in the biogenesis of lysosome-related organelles such as melanosomes.
Similarity
Belongs to the KXD1 family.
Mass
20.266 kDa
Sequence
MAEQVTEATASGVFCSRILNMVNSEDVNAIILAQRHMLDRFEKTNEMLLNFNGLSNTRLQQMSDRFAHHTRTLVEMKKDLDIIFRRIRMLKGKLAKQYPESFNNVHESPILEDDDDFDPTPRSAATTIATSEQSTESCDTSPSIISPAMSQDFEDLSQAPSDTPSVNGQILTDEEVVHED

Gene
KXD1
Protein
Biogenesis of lysosome-related organelles complex 1 subunit KXD1
Organism
Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37)
Length
178 amino acids
Function
Component of the biogenesis of lysosome-related organelles complex-1 (BLOC-1) involved in endosomal cargo sorting.
Similarity
Belongs to the KXD1 family.
Mass
20.217 kDa
Sequence
MDEHRSRTPSIDSRNYAIPEADYLPAGIDIDRNGVSESDDSSDDDAQSSLFPTESSGTLWMNQIQDTPMFDSSKFLFESVNNAINDIDFSESLAIQAKTSALINSKSRELKGLIKQLQEKVDYYNERFKRGAVVSSQLKVNLQMLSKRIATLDDLFSKQFPIEYNQSKEKVMERTLND

Gene
Kxd1
Protein
KxDL motif-containing protein 1
Organism
Mus musculus
Length
177 amino acids
Function
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (By similarity). May also be involved in the biogenesis of lysosome-related organelles such as melanosomes (PubMed:22554196).
Similarity
Belongs to the KXD1 family.
Mass
19.977 kDa
Sequence
MDTPDSASRVFCGRFLSMVNTDDVNAIILAQKNMLDRFEKTNEMLLNFNNLSSVRLQQMSERFMHHTRTLVDMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEGSFLEDEDEDPIPPSITTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHIQPGSPAINGHRQTDDEEETHEE

Gene
Kxd1
Protein
KxDL motif-containing protein 1
Organism
Rattus norvegicus
Length
177 amino acids
Function
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. May also be involved in the biogenesis of lysosome-related organelles such as melanosomes.
Similarity
Belongs to the KXD1 family.
Mass
19.913 kDa
Sequence
MDTPDSASRVFCGRFLSMVNTDDVNAIILAQKNMLDRFEKTNEMLLNFNNLSSVRLQQMSERFMHHTRTLVDMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEGSLLEDEDEDPVPPSITTTIATSEQSTGSCDTSPDTASPSFSPGFEDLSHIRPGSPAINGHSQTDDEEETREE

Gene
KXD1
Protein
KxDL motif-containing protein 1
Organism
Bos taurus
Length
176 amino acids
Function
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor. May also be involved in the biogenesis of lysosome-related organelles such as melanosomes.
Similarity
Belongs to the KXD1 family.
Mass
19.635 kDa
Sequence
MDPPDSASRVFSSRILSMVNADDVSAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMNERFLHHTRTLVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEASLLEDEDEDPIPPSTTTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHIRPGSPAINGRSHTDDEEMPGE

Gene
KXD1
Protein
KxDL motif-containing protein 1
Organism
Homo sapiens
Length
176 amino acids
Function
As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (PubMed:25898167). May be involved in the biogenesis of lysosome-related organelles such as melanosomes (By similarity).
Similarity
Belongs to the KXD1 family.
Mass
19.668 kDa
Sequence
MDLPDSASRVFCGRILSMVNTDDVNAIILAQKNMLDRFEKTNEMLLNFNNLSSARLQQMSERFLHHTRTLVEMKRDLDSIFRRIRTLKGKLARQHPEAFSHIPEASFLEEEDEDPIPPSTTTTIATSEQSTGSCDTSPDTVSPSLSPGFEDLSHVQPGSPAINGRSQTDDEEMTGE