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KRTAP5-3

Gene
KRTAP5-3
Protein
Keratin-associated protein 5-3
Organism
Homo sapiens
Length
238 amino acids
Function
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Similarity
Belongs to the KRTAP type 5 family.
Mass
22.106 kDa
Sequence
MGCSGCSGGCGSSCGGCGSSCGGCGSGYGGCGSGCCVPVCCCKPVCCCVPACSCSSCGSCGGSKGVCGSCGGCKGGCGSCGGSKGGCGSSCCVPVCCSSSCGSCGGSKGVCGFRGGSKGGCGSCGCSQCSCYKPCCCSSGCGSSCCQSSCCKPSCSQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCCSQSSCCKPCCCSSGCGSSCCQSSCCKPCSSQSSCCVPICCQCKI

Gene
Krtap5-3
Protein
Keratin-associated protein 5-3
Organism
Mus musculus
Length
196 amino acids
Function
In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.
Similarity
Belongs to the KRTAP type 5 family.
Mass
17.777 kDa
Sequence
MSCCGCCGGCGSSCCKPVCCCVPVCSCSSCGGCKGGCSSCGGCGSCGGCKGGCGSCGGCGSCGGCKGGCGSCGGCGSCGGCKGGCGSCGGCGSCGGCKGGCGSCGGCGSCGGCKGGCSSCGGCGSCGAASPSCVSPAAASPAVQALLLPVQLLQALLLPAQLLLVQLLLSLLLLHDCGSSCCPMSCSLPIYCQREI