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KMP-11

Gene
KMP-11
Protein
Kinetoplastid membrane protein 11
Organism
Leishmania donovani
Length
92 amino acids
Function
May be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules. May be involved in parasite mobility and attachment to the surface of the host cell. Strongly stimulates T-cell proliferation and is thought to play a role in the immunology of leishmaniasis.
Similarity
Belongs to the KMP-11 family.
Mass
11.262 kDa
Sequence
MATTYEEFSAKLDRLDQEFNRKMQEQNAKFFADKPDESTLSPEMREHYEKFERMIKEHTEKFNKKMHEHSEHFKQKFAELLEQQKAAQYPSK

Gene
KMP-11
Protein
Kinetoplastid membrane protein 11
Organism
Leishmania tropica
Length
92 amino acids
Function
May be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules. May be involved in parasite mobility and attachment to the surface of the host cell. Behaves as a strong immunogen during infection (By similarity).
Similarity
Belongs to the KMP-11 family.
Mass
11.235 kDa
Sequence
MATTYEEFSAKLDRLDEEFNRKMQEQNAKFFADKPDESTLSPEMKEHYEKFERMIKEHTEKFNKKMHEHSEHFKQKFAELLEQQKAAQYPSK

Gene
KMP-11
Protein
Kinetoplastid membrane protein 11
Organism
Trypanosoma brucei rhodesiense
Length
92 amino acids
Function
May be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules. May be involved in parasite mobility and attachment to the surface of the host cell. Behaves as a strong immunogen during infection (By similarity).
Similarity
Belongs to the KMP-11 family.
Mass
11.077 kDa
Sequence
MATTYEEFAAKLDRLDAEFAKKMEEQNKRFFADKPDEATLSPEMKEHYEKFEKMIQEHTDKFNKKMREHSEHFKAKFAELLEQQKNAQFPGK

Gene
KMP-11
Protein
Kinetoplastid membrane protein 11
Organism
Trypanosoma cruzi
Length
92 amino acids
Function
May be involved in the regulation of the cytoskeleton through interaction with the subpellicular microtubules. May be involved in parasite mobility and attachment to the surface of the host cell. Behaves as a strong immunogen during infection.
Similarity
Belongs to the KMP-11 family.
Mass
11.011 kDa
Sequence
MATTLEEFSAKLDRLDAEFAKKMEEQNKKFFADKPDESTLSPEMKEHYEKFEKMIQEHTDKFNKKMHEHSEHFKAKFAELLEQQKNAQFPGK