Protein
2-dehydro-3-deoxyphosphooctonate aldolase 2
Organism
Arabidopsis thaliana
Function
Catalyzes the stereospecific condensation of D-arabinose 5-phosphate and phosphoenolpyruvate to form 3-deoxy-D-manno-octulosonate 8-phosphate (KDO-8-phosphate) and inorganic phosphate. Involved in the biosynthesis of 3-deoxy-D-manno-octulosonate (KDO) which is an indispensable component of rhamnogalacturonan II (RG-II), a structurally complex pectic polysaccharide of the primary cell wall. RG-II is essential for the cell wall integrity of rapidly growing tissues and pollen tube growth and elongation.
Similarity
Belongs to the KdsA family.
Sequence
MANSASLLYDQLKVAEPFFLLAGPNVIESEEHVLRMAKSIKDISTKLGLPLVFKSSFDKANRTSSKSFRGPGMAEGLKILEKVKVAFDLPIVTDVHESSQCEAVGKVADIIQIPAFLCRQTDLLVAAAQSGKIINIKKGQFCGHSVMRNSAEKVRLAGNPNVMVCERGTMFGYNDLIVDPRNLEWMREADCPVVADITHSLQQPAGKKLDGGGVASGGLRELIPCIARTAVAVGVDGIFMEVHDDPLNAPVDGPTQWPLRHLEELLEELIAIASVTKGKQQFQIDLTPYRD