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JMJ30

Gene
JMJ30
Protein
Lysine-specific demethylase JMJ30
Organism
Arabidopsis thaliana
Length
429 amino acids
Function
Histone demethylase that demethylates 'Lys-36' (H3K36me) of histone H3 with a specific activity for H3K36me3 and H3K36me2 (PubMed:25132385). No activity on H3K36me1 (PubMed:25132385). Involved in the control of flowering time by demethylating H3K36me2 at the FT locus and repressing its expression (PubMed:25132385). Acts within the central clock. Works in concert with TOC1 to promote the morning-phased clock genes CCA1 and LHY which function as components of the central oscillator.
Mass
48.075 kDa
Sequence
MSGATTASSGDHNNLRLPTPTLDAESQTLLQSISAEGGYAYARMAVLAVAGDQSAAEAARDMAWEQLHSGPWHSVLPVWRDAYSMACLHVAKIHFAAGEFGEALGALDMGLIMGGMLLRKDLHDSVLLVSSEARKMTKSLEEASGDFKGERLVPEVPVDVNEVRHVLANLQLLVLKILPCRSLTCKRVEKRSGLSLEGFLRDYYLPGTPVVITNSMAHWPARTKWNHLDYLNAVAGNRTVPVEVGKNYLCSDWKQELVTFSKFLERMRTNKSSPMEPTYLAQHPLFDQINELRDDICIPDYCFVGGGELQSLNAWFGPAGTVTPLHHDPHHNILAQVVGKKYIRLYPSFLQDELYPYSETMLCNSSQVDLDNIDETEFPKAMELEFMDCILEEGEMLYIPPKWWHYVRSLTMSLSVSFWWSNEAESSSS