JJJ1

Gene

JJJ1

Protein

DNAJ protein JJJ1 homolog

Organism

Arabidopsis thaliana

Length

630 amino acids

Mass

72.476 kDa

Sequence

MASSSRSEKRCHYEVLGISKESSPDEIRSSYRRLALQRHPDKLMKAAGLSEAEATAQFQELVHAYEVLSDPKERAWYDSHRSQILFADHSSAGGSKSGGSVPDLFAFFSPTVYSGYSDTGKGFYKVYYDVFNSVYLNEIKFARTLGLRMDSVREAPIMGNLESPYAQVTAFYNYWLGFCTVMDFCWVDEYDVMGGPNRKSRRMMEEENKKSRKKAKREYNDTVRGLAEFVKKRDKRVIDMLVKKNAEMEKKKEEERERKKKMEKERLERAMNYEEPEWAKAHEGEDEGAGLSELEEEDDDAKRKNEQLYCIVCSKKFKSEKQWKNHEQSKKHKEKVAELRESFTDYEEENEEEEIDGPLDSPESVEELHEKLQEELNIDNEERDVKKEVVGEADETDDEYFVAEEDMQGSSESEDEDDEMTLLKKMVSGQKNKQKNVVSKEEDEDETEVEIEGDTAEFSEFDNQKSTGRNKEAKEERNKQNAGNDMADDTSKVQIPGEGGNPDENMNATESASGALADSQKDEANSMEYDNRKSTGRRRRSKKGKDKNNQGELNEKSSEADDTQYVNRDMESQDYKKAPRSKKSTRGMKTKGTTKKNSSNECDRCGEEFESRTKLHKHLADSGHATVKSR

Protein

DNAJ protein JJJ1 homolog: JJJ1

Gene

JJJ1

Protein

Negative regulator of PDR1-mediated fluconazole resistance JJJ1

Organism

Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65)

Length

623 amino acids

Function

Acts as a negative regulator of fluconazole resistance, primarily through down-regulation of the ABC transporter gene CDR1 via inactivation of the PDR1 transcriptional pathway.

Mass

72.885 kDa

Sequence

MKTCYYDLLEVRSDASDLDLKKAYRRKALQYHPDKNPDNVEEATTIFAEIRAAYEVLSDPQERAWYDSHKEQILSDTPLNPNDEDDDYVVDSTVTGVTTEELMMFFNSSLYTSIDNSPAGFYQIAGKVFAKIAKDEVSWGLRLGLDGYKNYKDMEFEEHINSRGYILACDSSKANLSNLLFPIFGYSSTSYEELKLFYTKWSSFNTLKSFTWKDEYMYSRNYDRRTKREINKRNEKARAKAKEEYIKTVKRYVNFIKKLDQRMKEGAKKAAEKRLADERLRKENEMKLRKERLNNEQGAQFHLQSWQTIDQENWKELEKQYEKEFEKRNVDKDDELIGHEFTKNQFQTNNNSQHEDVDEIIIYDCFICKKSFKSEKQLENHIKTKLHKRNLDRVQKEMKKDSMALGLDELSDYNDFDSAESETEKLYSGMDLNDIDAELKKIEEQLAQSSVTDSEDFTDDNNDTEDQNSLVDKLSNTNYDIEIDDEINDDTNEEVQISGADNSETQNAEQDHDSNGDSEEEKEDELTRILRELEESKTSRSNFSDSDEEWSNKKKTKAKKKKNKANTPDKQPVTANKNDAKEVCGECRAEFESRNQLFSHIQTEGHVSPLSKVKKGKRSKKNK

Protein

Negative regulator of PDR1-mediated fluconazole resistance JJJ1: JJJ1

Gene

JJJ1

Protein

J protein JJJ1

Organism

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

Length

590 amino acids

Mass

68.783 kDa

Sequence

MKTCYYELLGVETHASDLELKKAYRKKALQYHPDKNPDNVEEATQKFAVIRAAYEVLSDPQERAWYDSHKEQILNDTPPSTDDYYDYEVDATVTGVTTDELLLFFNSALYTKIDNSAAGIYQIAGKIFAKLAKDEILSGKRLGKFSEYQDDVFEQDINSIGYLKACDNFINKTDKLLYPLFGYSPTDYEYLKHFYKTWSAFNTLKSFSWKDEYMYSKNYDRRTKREVNRRNEKARQQARNEYNKTVKRFVVFIKKLDKRMKEGAKIAEEQRKLKEQQRKNELNNRRKFGNDNNDEEKFHLQSWQTVKEENWDELEKVYDNFGEFENSKNDKEGEVLIYECFICNKTFKSEKQLKNHINTKLHKKNMEEIRKEMEEENITLGLDNLSDLEKFDSADESVKEKEDIDLQALQAELAEIERKLAESSSEDESEDDNLNIEMDIEVEDVSSDENVHVNTKNKKKRKKKKKAKVDTETEESESFDDTKDKRSNELDDLLASLGDKGLQTDDDEDWSTKAKKKKGKQPKKNSKSTKSTPSLSTLPSSMSPTSAIEVCTTCGESFDSRNKLFNHVKIAGHAAVKNVVKRKKVKTKRI

Protein

J protein JJJ1: JJJ1