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JDP2

Gene
JDP2
Protein
Jun dimerization protein 2
Organism
Homo sapiens
Length
163 amino acids
Function
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin.
Similarity
Belongs to the bZIP family. ATF subfamily.
Mass
18.704 kDa
Sequence
MMPGQIPDPSVTTGSLPGLGPLTGLPSSALTVEELKYADIRNLGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKQERQQLILMLNRHRPTCIVRTDSVKTPESEGNPLLEQLEKK

Gene
Jdp2
Protein
Jun dimerization protein 2
Organism
Mus musculus
Length
163 amino acids
Function
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1, such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin (By similarity).
Similarity
Belongs to the bZIP family. ATF subfamily.
Mass
18.675 kDa
Sequence
MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTPESEGNPLLEQLDKK

Gene
Jdp2
Protein
Jun dimerization protein 2
Organism
Rattus norvegicus
Length
163 amino acids
Function
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. Involved in a variety of transcriptional responses associated with AP-1, such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. Can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. May control transcription via direct regulation of the modification of histones and the assembly of chromatin (By similarity).
Similarity
Belongs to the bZIP family. ATF subfamily.
Mass
18.675 kDa
Sequence
MMPGQIPDPSVTAGSLPGLGPLTGLPSSALTTEELKYADIRNIGAMIAPLHFLEVKLGKRPQPVKSELDEEEERRKRRREKNKVAAARCRNKKKERTEFLQRESERLELMNAELKTQIEELKLERQQLILMLNRHRPTCIVRTDSVRTPESEGNPLLEQLDKK

Gene
jdp2
Protein
Jun dimerization protein 2
Organism
Danio rerio
Length
156 amino acids
Function
Component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins.
Similarity
Belongs to the bZIP family. ATF subfamily.
Mass
17.915 kDa
Sequence
MMPGQIPDPLVTAGSLPSVGPLAGFPATTLTEQLKLAELYRLGTVLSPLMLNRHAKRPFDAIKSEDDDDDERKKRRREKNKVAAARCRNRKKERTDFLQKESERLEMLNSDLKSQIEELKSERQQLIVMLNLHRPTCIVRTDSVKSDEHPLEPRED