Protein
COP9 signalosome complex subunit 5
Organism
Candida albicans (strain SC5314 / ATCC MYA-2876)
Function
Catalytic Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes.
Similarity
Belongs to the peptidase M67A family. CSN5 subfamily.
Sequence
MTCLDELAHSLESKSDTTNFKTRNSKIKTIDLYQQNELSGKHPQDQDKFYRLPAIDPIARDKKPWKEDINYFNKCYISSLALMKMCTHAQTGGSIEIMGMLVGKISGHSIIVMDTYRLPVEGTETRVNAQNEAYTYMVEYLTERQQLSNGKNEENIVGWYHSHPGYGCWLSGIDVSTQSLNQGFQDPYLAIVVDPVKTLKQGKVEIGAFRTYPEGSQQQPSMTNKTRKDQNKPHNSGANANRKILPKSKQKDFGSHADKYYSLDIEIFTSSWDDKVIEMLKDEDSLTWMKNLLVDSNNNDKILGIRKDEIRSIELIKNYELISQGNHNADEGETIFDLIEQLKIQANTPKFMLDKLTTMKFDSTFESVLYKRLLKKTQKSTTTKKNRKDLSTDIDDETMLDESDLEKNVGTGGIETSISSDDDDEEEEGEGEGNSSSRRDNNNNEVEEGPTDEVDSEYANEELLEEVGALENYNFNDLLENKSANKFLRSEQKIKHKNRPIHQRMDNSSMISEWNRLGHQQQHMPADYPYQWSSNVANLVKTSKTNRRRERLHRLQGASIDNKKQFELGLHGSPESKAKSANLVKLAKSIGLNEVFDLITLDAQQKLFG