Protein
Interleukin-22 receptor subunit alpha-2
Organism
Rattus norvegicus
Function
Receptor for IL22. Binds to IL22, prevents interaction with the functional IL-22R complex and blocks the activity of IL22 (in vitro). May play an important role as an IL22 antagonist in the regulation of inflammatory responses.
Similarity
Belongs to the type II cytokine receptor family.
Sequence
MPKHCFLGLLIMLLTTATETQPAHVSLKPQKVQFQSRNFHNILHWQPGNSLTSNGSVYFVQYKTYGQGQWKDKNDCWGTTALFCDLTKETLDPYEPYYGRVMMAWAGSYSEWTRTPRFTPWWETKLDPPVVTITRVNASLRVRLRPPELPHRNQTGKNTSMENYYNLVYRVSIINNSLEKEQKAYEGTQRAVEIQGLTPHCSYCVVAEMYQPMFDRRSPRSKERCVQIP