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IL1RN

Gene
Il1rn
Protein
Interleukin-1 receptor antagonist protein
Organism
Mus musculus
Length
178 amino acids
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Similarity
Belongs to the IL-1 family.
Mass
20.274 kDa
Sequence
MEICWGPYSHLISLLLILLFHSEAACRPSGKRPCKMQAFRIWDTNQKTFYLRNNQLIAGYLQGPNIKLEEKIDMVPIDLHSVFLGIHGGKLCLSCAKSGDDIKLQLEEVNITDLSKNKEEDKRFTFIRSEKGPTTSFESAACPGWFLCTTLEADRPVSLTNTPEEPLIVTKFYFQEDQ

Gene
Il1rn
Protein
Interleukin-1 receptor antagonist protein
Organism
Rattus norvegicus
Length
178 amino acids
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
20.282 kDa
Sequence
MEICRGPYSHLISLLLILLFRSESAGHPAGKRPCKMQAFRIWDTNQKTFYLRNNQLIAGYLQGPNTKLEEKIDMVPIDFRNVFLGIHGGKLCLSCVKSGDDTKLQLEEVNITDLNKNKEEDKRFTFIRSETGPTTSFESLACPGWFLCTTLEADHPVSLTNTPKEPCTVTKFYFQEDQ

Gene
IL1RN
Protein
Interleukin-1 receptor antagonist protein
Organism
Equus caballus
Length
177 amino acids
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Similarity
Belongs to the IL-1 family.
Mass
20.46 kDa
Sequence
MEIRRRSVRHLISLLLFLFYSETACHPLGKRPCKMQAFRIWDVNQKTFYMRNNQLVAGYLQESNTKLQEKIDVVPIEPDALFLGLHGRKLCLACVKSGDEIRFQLEAVNITDLSKNKEENKRFTFIRSNSGPTTSFESAACPGWFLCTAQEADRPVSLTNKPKESFMVTKFYLQEDQ

Gene
IL1RN
Protein
Interleukin-1 receptor antagonist protein
Organism
Homo sapiens
Length
177 amino acids
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure.
Mass
20.055 kDa
Sequence
MEICRGLRSHLITLLLFLFHSETICRPSGRKSSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSENRKQDKRFAFIRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDEGVMVTKFYFQEDE

Gene
IL1RN
Protein
Interleukin-1 receptor antagonist protein
Organism
Macaca fascicularis
Length
177 amino acids
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
19.892 kDa
Sequence
MEICRGLGSHLICLLLFLFHSETVGRPSGRKPSKMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNVNLEEKIDVVPIEPHALFLGIHGGKMCLSCVKSGDETRLQLEAVNITDLSKNRKQDKRFAFVRSDSGPTTSFESAACPGWFLCTAMEADQPVSLTNMPDKGVMVTKFYFQEDE

Gene
IL1RN
Protein
Interleukin-1 receptor antagonist protein
Organism
Sus scrofa
Length
177 amino acids
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
20.093 kDa
Sequence
MEVSRYLCSYLISFLLFLFHSETACHPLGKRPCRMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNTKLEEKIDVVPVEPHFVFLGIHGGKLCLSCVKSGDEMKLQLDAVNITDLRKNSEQDKRFTFIRSDSGPTTSFESAACPGWFLCTALEADQPVGLTNTPKAAVKVTKFYFQQDQ

Gene
IL1RN
Protein
Interleukin-1 receptor antagonist protein
Organism
Oryctolagus cuniculus
Length
177 amino acids
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Similarity
Belongs to the IL-1 family.
Mass
20.214 kDa
Sequence
MRPSRSTRRHLISLLLFLFHSETACRPSGKRPCRMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNAKLEERIDVVPLEPQLLFLGIQRGKLCLSCVKSGDKMKLHLEAVNITDLGKNKEQDKRFTFIRSNSGPTTTFESASCPGWFLCTALEADQPVSLTNTPDDSIVVTKFYFQEDQ

Gene
IL1RN
Protein
Interleukin-1 receptor antagonist protein
Organism
Tursiops truncatus
Length
177 amino acids
Function
Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
19.923 kDa
Sequence
MEVCRCHHGYLISLLLFLFHSETACYPLGKRPCEMQAFRIWDVNQKTFYLRNNQLVAGYLQGPNTKLEEKIDVVPIEPHAMFLGIHGGKLCLACVKSGDEIKLGLEPVNITDLNSSKEEDKRFAFIRSDSGPTTSFESAACPGWFLCTALETDQPVGLTNTPQDAVQVTKFYFQQDQ

Gene
IL1RN
Protein
Interleukin-1 receptor antagonist protein
Organism
Canis lupus familiaris
Length
176 amino acids
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity (By similarity).
Similarity
Belongs to the IL-1 family.
Mass
19.922 kDa
Sequence
METCRCPLSYLISFLLFLSHSETACRPLGKRPCRMQAFRIWDVNQKTFYLRNNQLVAGYLQGSNTKLEEKLDVVPVEPHAVFLGIHGGKLCLACVKSGDETRLQLEAVNITDLSKNKDQDKRFTFILSDSGPTTSFESAACPGWFLCTALEADRPVSLTNRPEEAMMVTKFYFQKE

Gene
IL1RN
Protein
Interleukin-1 receptor antagonist protein
Organism
Bos taurus
Length
174 amino acids
Function
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
Similarity
Belongs to the IL-1 family.
Mass
19.926 kDa
Sequence
MDIYIHGYLICLLLFLFRSETACHPLGKRRCEMQAFRIWDVNQKIFYLRNNQLVAGYLQGPNTKLEEKIDVVPIEPHTMFLGIHGGKLCLACVKSGDEIKLKLEAVNITDLNQNREQDKRFAFIRFDNGPTTSFESAACPGWFLCTSLEADQPVGLTNMPTEALKVTKFYFQQD